ArticleClinical oral investigations2018
Glass ionomer cement inhibits secondary caries in an in vitro biofilm model.
Article in Clinical oral investigations, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 67 citations in OpenAlex.
- In vivo study of the behavior of glass ionomer restorations in patients with special needs.Medicina oral, patologia oral y cirugia bucal · 2024Trial
- Trial
- Recent Advances in Caries Prevention and Non-Invasive Management: From Ecological Modulation to Precision Interventions.Dentistry journal · 2026Review
- Efficacy of resin-based and glass-ionomer sealants in retention, fissure penetration, and occlusal caries inhibition: an in vitro study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Article
- Evaluation of the bond strength of glass ionomer cement modified with fluoride-loaded chitosan nanoparticles to caries-affected dentin.BMC oral health · 2025Article
- Efficacy of sealants with surface pre-reacted glass (S-PRG) in retention, fissure penetration and occlusal caries Inhibition : Short title: efficacy of S-PRG sealants.Clinical oral investigations · 2025Article
- Clinical Difficulties Related to Direct Composite Restorations: A Multinational Survey.International dental journal · 2025Article
- The evaluation of internal adaptation of glass ionomer restorations applied after the use of different cavity conditioners in primary teeth: an in-vitro study.BMC oral health · 2025Article
- The formation of cariogenic plaque to contemporary adhesive restorative materials: an in vitro study.Odontology · 2024Article
- Surface Prereacted Glass Ionomer Varnish as a Multifaceted Anticaries Agent: Investigating its Inhibitory Effects on Demineralization and Biofilm Formation on Primary Tooth Enamel.International journal of clinical pediatric dentistry · 2024Article
- Retrospective Clinical Evaluation of RMGIC/GIC Class V Restorations.Dentistry journal · 2023Article
- Bonding performance of glass ionomer cement to carious dentin treated with different surface treatment protocols using silver diamine fluoride.Scientific reports · 2023Article
- Inhibition of Caries around Restoration by Ion-Releasing Restorative Materials: An In Vitro Optical Coherence Tomography and Micro-Computed Tomography Evaluation.Materials (Basel, Switzerland) · 2023Article
- Release Kinetics of Monomers from Dental Composites Containing Fluoride-Doped Calcium Phosphates.Pharmaceutics · 2023Article
- Modification of glass-ionomer cement properties by quaternized chitosan-coated nanoparticles.Odontology · 2023Article
- Dental Luting Cements: An Updated Comprehensive Review.Molecules (Basel, Switzerland) · 2023Review
- The impact of an alkasite restorative material on the pH of Streptococcus mutans biofilm and dentin remineralization: an in vitro study.BMC oral health · 2022Article
- Effect of the Addition of Varying Concentrations of Silver Nanoparticles on the Fluoride Uptake and Recharge of Glass Ionomer Cement.Nanomaterials (Basel, Switzerland) · 2022Article
- Evaluation of the Mechanical Properties of Three Resin-Modified Glass-Ionomer Materials.BioMed research international · 2022Article
- The reciprocal interaction between fluoride release of glass ionomers and acid production ofJournal of oral microbiology · 2022Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe objective of this study was to investigate the effect of different glass ionomer cements on secondary caries inhibition in a fully automated in vitro biofilm model. MATERIALS AND
methodsOne hundred and twenty-four extracted third molars received class V cavities and were filled with one conventional (Ketac Molar/KM), and two resin-modified glass ionomer cements (Photac Fil/PF, Ketac N100/KN, 3M Espe). A bonded resin composite (Single Bond Plus/Filtek Supreme XTE) served as control. After 14 days water storage at 37 °C, specimens were thermocycled (10,000 × 5/55 °C). Over a period of 10 days, specimens were subjected to cariogenic challenge for 3/4/6 h/day. Demineralization was caused by Streptococcus mutans (DSM 20523) alternatingly being rinsed over specimens using artificial saliva. After biological loading, teeth were cut longitudinally and demineralization depths were evaluated at the margins and at a distance of 0.5 mm from the margins using fluorescence microscopy. Marginal quality was investigated under a SEM at ×200 magnification.
resultsFour-hour demineralization depths were for enamel margins (EM), enamel (E), dentin margin (DM), and dentin (D) (μm ± SD): KM: EM 12 ± 8, E 33 ± 7, DM 56 ± 11, D 79 ± 6; PF: EM 19 ± 13, E 34 ± 13, DM 53 ± 10, D 77 ± 12; and KN: EM 26 ± 5, E 38 ± 6, DM 57 ± 11, D 71 ± 7. For all glass ionomer cements (GICs), demineralization depth at the margins was less compared to 0.5 mm distance, with demineralization depth having been correlated to duration of cariogenic challenge (ANOVA [mod. LSD, p < 0.05]). Compared to the bonded resin composite, all GICs exhibited caries inhibition at restoration margins in enamel and dentin.
conclusionsFluoride-releasing GIC materials exhibit a secondary caries inhibiting effect in vitro. CLINICAL RELEVANCE: Glass ionomer cements have a higher secondary caries inhibiting effect than resin composites.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.