ArticleTherapeutic advances in psychopharmacology2017
Long-term use of benzodiazepines in older patients in Germany: a retrospective analysis.
Article in Therapeutic advances in psychopharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Barriers and enablers for deprescribing benzodiazepine receptor agonists in older adults: a systematic review of qualitative and quantitative studies using the theoretical domains framework.Implementation science : IS · 2022Pooled it
- Trajectories Associated With the Use and Deprescription of Benzodiazepines and Z-Drugs in a Network of Geriatric Outpatient Clinics.Pharmacoepidemiology and drug safety · 2026Article
- Pharmacotherapy of psychiatric inpatients with mental and behavioral disorders caused by sedatives or hypnotics (F13): Results from an observational pharmacovigilance program between 2000 and 2017.Addiction science & clinical practice · 2025Observational
- Article
- Long-term benzodiazepine prescriptions in community psychiatry clinics.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2024Article
- Trajectories of Benzodiazepine Use among Older Adults from a Concordance-with-Guidelines Perspective: A Nationwide Cohort Study.Drugs & aging · 2023Article
- Factors associated with long-term benzodiazepine and Z-drug use across the lifespan and 5-year temporal trajectories among incident users: a Swedish nationwide register-based study.European journal of clinical pharmacology · 2023Article
- The Characteristics of Benzodiazepine Prescribing in the Republic of Srpska, Bosnia and Herzegovina.Medicina (Kaunas, Lithuania) · 2022Article
- The patterns and burden of multimorbidity in geriatric patients with prolonged use of addictive medications.Aging clinical and experimental research · 2021Article
- Prescribing Pattern of Hypnotic Medications in Patients Initiating Treatment at Japanese Hospitals: A Nationwide, Retrospective, Longitudinal, Observational Study Using a Claims Database.Drugs - real world outcomes · 2021Article
- Benzodiazepine and Z-Drug Use in Switzerland: Prevalence, Prescription Patterns and Association with Adverse Healthcare Outcomes.Neuropsychiatric disease and treatment · 2021Article
- Trends in benzodiazepine receptor agonists use and associated factors in the Belgian general older population: analysis of the Belgian health interview survey data.Therapeutic advances in psychopharmacology · 2021Article
- Use of benzodiazepines and z-drugs not compliant with guidelines and associated factors: a population-based study.European archives of psychiatry and clinical neuroscience · 2020Article
- Patterns of benzodiazepine prescription among older adults in Switzerland: a cross-sectional analysis of claims data.BMJ open · 2020Article
- Benzodiazepine usage and patient preference for alternative therapies: A descriptive study.Health science reports · 2019Article
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- Article
- The Problem of Benzodiazepine Use and Its Extent in the Driver Population: A Population-Based Registry Study.Frontiers in pharmacology · 2018Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to analyze the prevalence of long-term benzodiazepine use in older adults treated in general and neuropsychiatric practices in Germany.
methodsThis study included 32,182 patients over the age of 65 years who received benzodiazepine prescriptions for the first time between January 2010 and December 2014 in general and neuropsychiatric practices in Germany. Follow up lasted until July 2016. The main outcome measure was the proportion of patients treated with benzodiazepines for >6 months.
resultsThe proportion of patients with benzodiazepine therapy for >6 months increased with age (65-70 years: 12.3%; 71-80 years: 15.5%; 81-90 years: 23.7%; >90 years: 31.6%) but did not differ significantly between men (15.5%) and women (17.1%). The proportion of patients who received benzodiazepines for >6 months was higher among those with sleep disorders (21.1%), depression (20.8%) and dementia (32.1%) than among those with anxiety (15.5%). By contrast, this proportion was lower among people diagnosed with adjustment disorders (7.7%) and back pain (3.8%).
conclusionOverall, long-term use of benzodiazepines is common in older people, particularly in patients over the age of 80 and in those diagnosed with dementia, sleep disorders, or depression.
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