Observational studyInternational journal of chronic obstructive pulmonary disease2017
Active smoking and COPD phenotype: distribution and impact on prognostic factors.
Observational study in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Pooled it
- Sociodemographic differences in clinical phenotypes among patients with COPD: a latent class analysis.BMJ open respiratory research · 2026Article
- Creating a next-generation phenotype library: the health data research UK Phenotype Library.JAMIA open · 2024Article
- Immunology in COPD and the use of combustible cigarettes and heated tobacco products.European journal of medical research · 2023Review
- Identification of Modifiable Risk Factors of Exacerbations Chronic Respiratory Diseases with Airways Obstruction, in Vietnam.International journal of environmental research and public health · 2022Article
- Survival Impact of Current-Smoking-Related COPD or COPD with Acute Exacerbation on Bladder Preservation through Concurrent Chemoradiotherapy for Muscle-Invasive Bladder Urothelial Carcinoma.Journal of personalized medicine · 2021Article
- Article
- Chronic Obstructive Pulmonary Disease Increases the Risk of Mortality among Patients with Colorectal Cancer: A Nationwide Population-Based Retrospective Cohort Study.International journal of environmental research and public health · 2021Article
- COPD Clinical Control: predictors and long-term follow-up of the CHAIN cohort.Respiratory research · 2021Observational
- COPD patients hospitalized with exacerbations have greater cognitive impairment than patients hospitalized with decompensated heart failure.Clinical interventions in aging · 2019Article
- The outcome and the influencing factors of the age of onset in post-mortem of chronic bronchitis patients: a retrospective study.International journal of chronic obstructive pulmonary disease · 2018Article
- Characteristics of COPD Phenotypes in Serbia.International journal of chronic obstructive pulmonary diseaseArticle
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSmoking can affect both the phenotypic expression of COPD and factors such as disease severity, quality of life, and comorbidities. Our objective was to evaluate if the impact of active smoking on these factors varies according to the disease phenotype. PATIENTS AND
methodsThis was a Spanish, observational, cross-sectional, multicenter study of patients with a diagnosis of COPD. Smoking rates were described among four different phenotypes (non-exacerbators, asthma-COPD overlap syndrome [ACOS], exacerbators with emphysema, and exacerbators with chronic bronchitis), and correlated with disease severity (body mass index, obstruction, dyspnea and exacerbations [BODEx] index and dyspnea grade), quality of life according to the COPD assessment test (CAT), and presence of comorbidities, according to phenotypic expression.
resultsIn total, 1,610 patients were recruited, of whom 46.70% were classified as non-exacerbators, 14.53% as ACOS, 16.37% as exacerbators with emphysema, and 22.40% as exacerbators with chronic bronchitis. Smokers were predominant in the latter 2 groups (58.91% and 57.67%, respectively,
conclusionActive smoking is more common among exacerbator phenotypes and appears to affect quality of life and dyspnea grade differently, depending on the clinical expression of the disease.
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