Observational studyInternational journal of chronic obstructive pulmonary disease2017
Glycated hemoglobin A1c-based adjusted glycemic variables in patients with diabetes presenting with acute exacerbation of chronic obstructive pulmonary disease.
Observational study in International journal of chronic obstructive pulmonary disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 21 citations in OpenAlex.
- Stress hyperglycemia ratio predicts adverse outcomes in emergency department patients with upper gastrointestinal bleeding.PloS one · 2026Article
- Association of stress hyperglycemia ratio with clinical outcomes in patients with chronic obstructive pulmonary disease and type 2 diabetes mellitus in intensive care units: a retrospective study.Journal of thoracic disease · 2025Article
- Increased Stress Hyperglycemia Ratio Predicts Poor Clinical Outcome in Critically Ill COPD Patients: A Retrospective Study.International journal of chronic obstructive pulmonary disease · 2025Article
- The Glycemic Ratio Is Strongly and Independently Associated With Mortality in the Critically Ill.Journal of diabetes science and technology · 2024Article
- Absolute Hyperglycemia versus Stress Hyperglycemia Ratio for the Prognosis of Hospitalized Patients with COVID-19 in the First Months of the Pandemic: A Retrospective Study.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023Article
- The relationship between glycated hemoglobin A1c levels and exacerbation status in the patients with chronic obstructive pulmonary disease.BMC research notes · 2022Article
- Stress hyperglycemia is predictive of clinical outcomes in patients with spontaneous intracerebral hemorrhage.BMC neurology · 2022Article
- Statins Associated with Better Long-Term Outcomes in Aged Hospitalized Patients with COPD: A Real-World Experience from Pay-for-Performance Program.Journal of personalized medicine · 2022Article
- Association of Pulmonary Function Decline over Time with Longitudinal Change of Glycated Hemoglobin in Participants without Diabetes Mellitus.Journal of personalized medicine · 2021Article
- Glycemia, Beta-Cell Function and Sensitivity to Insulin in Mildly to Critically Ill Covid-19 Patients.Medicina (Kaunas, Lithuania) · 2021Article
- Analysis of prevalence and prognosis of type 2 diabetes mellitus in patients with acute exacerbation of COPD.BMC pulmonary medicine · 2021Observational
- Stress Hyperglycemia and Complications Following Traumatic Injuries in Individuals With/Without Diabetes: The Case of Orthopedic Surgery.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Elevated Glycemic Gap Predicts Acute Respiratory Failure and In-hospital Mortality in Acute Heart Failure Patients with Diabetes.Scientific reports · 2019Article
- An elevated glycemic gap predicts adverse outcomes in diabetic patients with necrotizing fasciitis.PloS one · 2019Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute hyperglycemia is a common finding in patients presenting to emergency departments (EDs) with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Several studies have argued against the association between hyperglycemia at admission and adverse outcomes in patients with diabetes and an acute illness. Recent studies have shown that glucose-related variables (eg, glycemic gaps and stress hyperglycemia ratios) that are adjusted for glycated hemoglobin levels can indicate the severity of a variety of diseases. The objective of this study was to assess whether these hemoglobin A1c (HbA1c)-based adjusted average glycemic variables were associated with unfavorable outcomes in patients admitted to a hospital with AECOPD. We found that 1) pulmonary infection is a major risk factor for AECOPD; 2) a higher glycemic gap and modified stress hyperglycemia ratio were associated with the development of acute respiratory failure (ARF) in patients with diabetes admitted to an ED because of AECOPD; and 3) the glycemic gap and modified stress hyperglycemia ratio had superior discriminative power over acute hyperglycemia and HbA1c for predicting the development of ARF, although the HbA1c-adjusted glycemic variables alone were not independent risk factors for ARF.
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Registered trials
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