ArticleScientific reports2017
Proteinuria Detected by Urine Dipstick Test as a Risk Factor for Atrial Fibrillation: A Nationwide Population-Based Study.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 36 citations in OpenAlex.
- Improvement in proteinuria attenuates the occurrence of venous thromboembolism: A population-based cohort study.Scientific reports · 2025Article
- Albuminuria as a diagnostic criterion and a therapeutic target in heart failure and other cardiovascular disease.European journal of heart failure · 2025Review
- Proteinuria is risk factor for abdominal aortic aneurysm: a nationwide population-based study.BMC public health · 2025Article
- Instant and low-cost detection of urinary microalbumin using smartphone technology and a paper-based platform with a colorimetric ratio analysis.Scientific reports · 2025Article
- Proteinuria and the risk of Incident atrial fibrillation according to glycemic stages: a nationwide population-based cohort study.Cardiovascular diabetology · 2025Article
- Improved Proteinuria May Attenuate the Risk of Atrial Fibrillation: A Nationwide Population-Based Cohort Study.Journal of clinical medicine · 2024Article
- Inverse relationship between LDL-C/HDL-C ratio and atrial fibrillation in chronic kidney disease patients.Scientific reports · 2024Article
- Association of Chronic Kidney Disease With Atrial Fibrillation in the General Adult Population: A Nationwide Population-Based Study.Journal of the American Heart Association · 2023Article
- Association of immune-mediated inflammatory diseases with depression and anxiety in patients with type 2 diabetes: A nationwide population-based study.Frontiers in medicine · 2023Article
- Risk of all-cause and cause-specific mortality associated with immune-mediated inflammatory diseases in Korea.Frontiers in medicine · 2023Article
- Sex differences in the evaluation of proteinuria using the urine dipstick test.Frontiers in medicine · 2023Article
- Systemic sclerosis is a risk factor of incident psoriasis: results from a nationwide cohort study.Frontiers in immunology · 2023Article
- Effects of immune-mediated inflammatory diseases on cardiovascular diseases in patients with type 2 diabetes: a nationwide population-based study.Scientific reports · 2022Article
- Dipstick proteinuria and risk of type 2 diabetes mellitus: a nationwide population-based cohort study.Journal of translational medicine · 2021Article
- The Level of Urine Dipstick Proteinuria and Its Relation to the Risk of Incident Cholelithiasis.Journal of epidemiology · 2021Article
- Association of proteinuria with incident atrial fibrillation in the general Japanese population.Journal of cardiology · 2021Article
- Risk Factors for Chronic Kidney Disease in Older Adults with Hyperlipidemia and/or Cardiovascular Diseases in Taipei City, Taiwan: A Community-Based Cross-Sectional Analysis.International journal of environmental research and public health · 2020Article
- Review
- Impact of Hemoglobin Levels and Their Dynamic Changes on the Risk of Atrial Fibrillation: A Nationwide Population-Based Study.Scientific reports · 2020Article
- Effects of tolvaptan on urine output in hospitalized heart failure patients with hypoalbuminemia or proteinuria.Heart and vessels · 2018Article
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Proteinuria is one of the well-known risk factors for cardiovascular disease. However the impact of proteinuria on the incidence of atrial fibrillation (AF) is unclear. In this study, we investigated the association between proteinuria detected using urine dipstick test and the risk of AF. A total of 18,201,275 individuals were analyzed, who had no prior AF and had received biennial health checkups provided by the National Health Insurance Service between 2005 and 2008 in Korea. Incidences of AF were ascertained through the end of 2015. During a mean follow-up of 9.6 years, a total of 324,764 (1.8%) developed AF (1.86 per 1,000 person-years). In Cox regression models, proteinuria was associated with an increased risk of AF: adjusted HR and 95% CI of AF occurrence were 1.13 (1.10-1.16), 1.34 (1.31-1.38), 1.53 (1.48-1.58), 1.82 (1.71-1.94), and 1.86 (1.61-2.16) in individuals with trace, 1+, 2+, 3+, and 4+ proteinuria, respectively, compared with those without proteinuria. The result was consistent even after additional adjustment for estimated glomerular filtration rate. In addition, the risk of AF further increased or decreased according to the follow-up dipstick test results. Thus, proteinuria measured with a dipstick test might be considered a potent risk factor for AF development.
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