Evidence map›Paper›PMID 28740155›Full record

ArticleScientific reports2017

Trajectory of blood pressure change during pregnancy and the role of pre-gravid blood pressure: a functional data analysis approach.

Minxue Shen, Hongzhuan Tan, Shujin Zhou, Graeme N Smith, Mark C Walker, Shi Wu Wen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 73 citations in OpenAlex.

  1. The impact of low-dose aspirin on hemoglobin levels in pregnancy: A secondary analysis of a randomized controlled trial for prevention of hypertensive disorders of pregnancy.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Trial
  2. Blood pressure trajectories during pregnancy, labor, and postpartum period: a multicenter study in Japan.Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Observational
  3. Article
  4. Review
  5. The Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025).Hypertension research : official journal of the Japanese Society of Hypertension · 2026
    Article
  6. Article
  7. Blood Pressure and Late Pregnancy Circulating miRNAs in the MADRES Study.Journal of the American Heart Association · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Pregnancy Considerations in Tetralogy of Fallot.CJC pediatric and congenital heart disease · 2023
    Review
  16. Hypertension in Pregnancy: A Diagnostic and Therapeutic Overview.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023
    Review
  17. Chromogranin A: An Endocrine Factor of Pregnancy.International journal of molecular sciences · 2023
    Review
  18. Evidence of Nitric Oxide Impairment During Hypertensive Pregnancies.Advances in experimental medicine and biology · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Minxue ShenDepartment of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Hongzhuan TanDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, Hunan, China.
Shujin ZhouDepartment of Maternal and Child Health Care, Liuyang Maternal and Child Hospital, Liuyang, Hunan, China.
Graeme N SmithDepartment of Obstetrics and Gynecology, Queen's University, Kingston, Ontario, Canada.
Mark C WalkerOMNI Research Group, Department of Obstetrics and Gynecology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Shi Wu WenDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, Hunan, China. swwen@ohri.ca.
University of Ottawa · CACentral South University · CNLiuyang City Maternal and Child Health Hospital · CNOttawa Hospital Research InstituteQueen's University · CA

Funding

CIHR MOP115183
6 · The paper itself

Abstract

The study aims to examine the blood pressure (BP) trajectory during pregnancy and its association with pre-gravid BP level. In a pre-conception cohort study, newly-married women in Liuyang, China underwent pre-gravid measurements and were followed throughout the pregnancy. BP was measured at pre-conception and again throughout pregnancy. The functional principal component analysis was used to examine the trajectory of BP changes during pregnancy. A total of 1282 women with a singleton pregnancy who had both pre-conception and gestational BP measurements performed were included in the final analysis. The results showed that BP decreased significantly in early pregnancy and increased thereafter, without BP drop around 20 weeks of gestation. Pre-gravid BP level was inversely associated with the BP drop in early pregnancy, such that women with higher pre-gravid BP had greater BP drop at the beginning, while women with the lowest pre-gravid BP level demonstrated no obvious BP drop throughout the entire pregnancy.

Indexed as

AdultBlood PressureCase-Control StudiesFemaleHumansHypertensionHypotensionPregnancyPregnancy ComplicationsPregnancy OutcomeProspective Studies

Identifiers

PMID28740155
PMCPMC5524922
OpenAlexW2736683278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.