Evidence map›Paper›PMID 28739911›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Deacetylase activity of histone deacetylase 3 is required for productive

Kristy R Stengel, Kelly R Barnett, Jing Wang, Qi Liu, Emily Hodges, Scott W Hiebert, Srividya Bhaskara

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Recent Update of HDAC Inhibitors in Lymphoma.Frontiers in cell and developmental biology · 2020
    Review
  15. Circadian Regulation of Immunity Through Epigenetic Mechanisms.Frontiers in cellular and infection microbiology · 2020
    Review
  16. Article
  17. Article
  18. Integrative regulation of physiology by histone deacetylase 3.Nature reviews. Molecular cell biology · 2019
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kristy R StengelDepartment of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232.
Kelly R BarnettDepartment of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232.
Jing WangVanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37027.
Qi LiuVanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37027.
Emily HodgesDepartment of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232.
Scott W HiebertDepartment of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232; scott.hiebert@vanderbilt.edu.
Srividya BhaskaraDepartment of Radiation Oncology and Oncological Sciences, University of Utah School of Medicine and Huntsman Cancer Institute, Salt Lake City, UT84103.
Vanderbilt University · USHuntsman Cancer Institute · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI MATTHEW J TYSKA · 1995 to 2026
$172.8M
Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
BIOCHEMICAL &CHEMICAL TRAINING FOR CANCER RESEARCHT32CA009582 · NCI · VANDERBILT UNIVERSITY · PI David K Cortez · 1987 to 2026
$8.8M
Role of AML1-ETO in Acute LeukemiaR01CA064140 · NCI · VANDERBILT UNIVERSITY · PI HIEBERT, SCOTT W · 1994 to 2018
$5.7M
Training Program in Stem Cell and Regenerative Developmental BiologyT32HD007502 · NICHD · VANDERBILT UNIVERSITY · PI WRIGHT, CHRISTOPHER V · 1997 to 2022
$5.4M
Hdac3 as a therapeutic target in BCL6-dependent lymphomaR01CA164605 · NCI · VANDERBILT UNIVERSITY · PI HIEBERT, SCOTT W · 2012 to 2022
$3.9M
Histone deacetylases 1,2 and DNA repairR01CA188520 · NCI · UNIVERSITY OF UTAH · PI BHASKARA, SRIVIDYA · 2015 to 2019
$1.7M
Functions of Histone Ubiquitination and MethylationR01CA109355 · NCI · VANDERBILT UNIVERSITY · PI SUN, ZU-WEN · 2006 to 2010
$1.2M
Illumina Genome Analyzer IIS10RR028106 · NCRR · VANDERBILT UNIVERSITY · PI GEORGE, ALFRED L. · 2011 to 2011
$515k
NCI NIH HHS P30 CA068485NCI NIH HHS R01 CA064140NCI NIH HHS R01 CA109355NCI NIH HHS R01 CA164605NCI NIH HHS R01 CA188520NCI NIH HHS T32 CA009582NCRR NIH HHS S10 RR028106NICHD NIH HHS T32 HD007502NIDDK NIH HHS P30 DK058404
6 · The paper itself

Abstract

Histone deacetylase 3 (HDAC3) is the catalytic component of NCoR/SMRT corepressor complexes that mediate the actions of transcription factors implicated in the regulation of B-cell development and function. We crossed

Indexed as

AnimalsB-LymphocytesHistone Deacetylase 3Histone DeacetylasesImmunoglobulin Heavy ChainsImmunoglobulin Variable RegionMiceMice, TransgenicPoint MutationV(D)J RecombinationHistone Deacetylase 3Histone DeacetylasesImmunoglobulin Heavy ChainsImmunoglobulin Variable RegionB-cell developmentchromatin structureHDAC3histone deacetylaseVDJ recombination

Identifiers

PMID28739911
PMCPMC5559004
OpenAlexW2741181301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.