Evidence map›Paper›PMID 28739908›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Molecular mechanism of photoactivation of a light-regulated adenylate cyclase.

Mio Ohki, Ayana Sato-Tomita, Shigeru Matsunaga, Mineo Iseki, Jeremy R H Tame, Naoya Shibayama, Sam-Yong Park

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
7.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Structure ofeLife · 2022
    Article
  12. The nature of proton-coupled electron transfer in a blue light using flavin domain.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Review
  14. Article
  15. Review
  16. Photoactivated Adenylyl Cyclases: Fundamental Properties and Applications.Advances in experimental medicine and biology · 2021
    Review
  17. Photoreaction Mechanisms of Flavoprotein Photoreceptors and Their Applications.Advances in experimental medicine and biology · 2021
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Mio OhkiDrug Design Laboratory, Graduate School of Medical Life Science, Yokohama City University, Tsurumi, Yokohama 230-0045, Japan.
Ayana Sato-TomitaDivision of Biophysics, Department of Physiology, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan.
Shigeru MatsunagaCentral Research Laboratory, Hamamatsu Photonics KK, Hamakita-ku, Hamamatsu, Shizuoka 434-8601, Japan.
Mineo IsekiFaculty of Pharmaceutical Sciences, Toho University, Funabashi, Chiba 274-8510, Japan.
Jeremy R H TameDrug Design Laboratory, Graduate School of Medical Life Science, Yokohama City University, Tsurumi, Yokohama 230-0045, Japan.
Naoya ShibayamaDivision of Biophysics, Department of Physiology, Jichi Medical University, Shimotsuke, Tochigi 329-0498, Japan; park@yokohama-cu.ac.jp shibayam@jichi.ac.jp.
Sam-Yong ParkDrug Design Laboratory, Graduate School of Medical Life Science, Yokohama City University, Tsurumi, Yokohama 230-0045, Japan; park@yokohama-cu.ac.jp shibayam@jichi.ac.jp.
Yokohama City University · JPJichi Medical University · JPHamamatsu Photonics (Japan) · JPToho University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The photoactivated adenylate cyclase (PAC) from the photosynthetic cyanobacterium

Indexed as

Adenylyl CyclasesAllosteric SiteBacterial ProteinsCatalytic DomainCell LineCrystallography, X-RayCyanobacteriaCyclic AMPFlavinsHumansLightOptogeneticsOscillatoriaProtein DomainsProtein Structure, TertiaryAdenylyl CyclasesBacterial ProteinsCyclic AMPFlavinsallosteryBLUF domaincAMPoptogeneticsphotoactivation

Identifiers

PMID28739908
PMCPMC5559023
OpenAlexW2740340817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.