Trial reportProceedings of the National Academy of Sciences of the United States of America2017
Mapping of human brown adipose tissue in lean and obese young men.
Trial report in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04385615 (Effect of Fasting Mimicking Diet on the Activation of Beige/Brown Adipose Tissue in Humans), which is not on this map. Cited by 293 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Fasting Mimicking Diet on the Activation of Beige/Brown Adipose Tissue in Humans
Who cites it
293 citing papers in PubMed, 1 synthesis or guideline pooled it, 517 citations in OpenAlex.
- Effect of habitual cold exposure on brown adipose tissue activity in Arctic adults: a systematic review.International journal of circumpolar health · 2025Pooled it
- Fecal microbiota composition is related to brown adipose tissueJournal of endocrinological investigation · 2023Trial
- The Infrared Thermography Toolbox: An Open-access Semi-automated Segmentation Tool for Extracting Skin Temperatures in the Thoracic Region including Supraclavicular Brown Adipose Tissue.Journal of medical systems · 2022Trial
- No evidence of brown adipose tissue activation after 24 weeks of supervised exercise training in young sedentary adults in the ACTIBATE randomized controlled trial.Nature communications · 2022Trial
- Cold-Induced Thermogenesis Shows a Diurnal Variation That Unfolds Differently in Males and Females.The Journal of clinical endocrinology and metabolism · 2022Trial
- Brown adipose tissues mediate the metabolism of branched chain amino acids during the transitioning from hyperthyroidism to euthyroidism (TRIBUTE).Scientific reports · 2022Trial
- Metabolic effects of brown fat in transitioning from hyperthyroidism to euthyroidism.European journal of endocrinology · 2021Trial
- 6 weeks of fartlek-style endurance training does not alter physiological responses to mild cold exposure but attenuates the cold-induced plasma noradrenaline response: A randomized, matched control trial.Journal of clinical & translational endocrinology · 2026Article
- Association between brown adipose tissue activity and clinical outcomes in melanoma: a retrospective PET/CT analysis.Immuno-oncology technology · 2026Article
- Exercise and Fat: A Primer.Sports medicine - open · 2026Review
- Transferrin receptor 1-mediated iron uptake supports thermogenic activation in human cervical-derived adipocytes.FEBS letters · 2026Article
- Transcutaneous allicin oleogel restores energy homeostasis for obesity treatment.Acta pharmacologica Sinica · 2026Article
- Transcriptomic profiling of human brown and white adipose tissue depots.Nature communications · 2026Article
- Article
- Palmitoylethanolamide in Human and Animal Obesity.Molecules (Basel, Switzerland) · 2026Review
- PCPE-1 promotes cardiac fibrosis with aging and obesity.JCI insight · 2026Article
- Junctophilin-2-orchestrated calcium signalosome regulates brown adipocyte thermogenesis and energy metabolism.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Adipocyte Pten Inhibition Improves Metabolic Health Associated with Expanded Lipid Storage Capacity and Reduced Inflammation.bioRxiv : the preprint server for biology · 2026Article
- Cathepsins as Core Players in Obesity Pathogenesis: Emerging Therapeutic Targets.Biomolecules · 2026Review
- Brown Adipose Tissue and Metabolic Markers Differ Between Greenlanders and Danes With Cold Activation.The Journal of clinical endocrinology and metabolism · 2026Article
233 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
14 authors at 2 institutions in 2 countries.
Funding
Abstract
Human brown adipose tissue (BAT) can be activated to increase glucose uptake and energy expenditure, making it a potential target for treating obesity and metabolic disease. Data on the functional and anatomic characteristics of BAT are limited, however. In 20 healthy young men [12 lean, mean body mass index (BMI) 23.2 ± 1.9 kg/m
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.