ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2017
Long-term morbidity and mortality in patients without early complications after stroke or transient ischemic attack.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Inconsistent Classification of Mild Stroke and Implications on Health Services Delivery.Archives of physical medicine and rehabilitation · 2020Pooled it
- Program of Rehabilitative Exercise and Education to Avert Vascular Events After Non-Disabling Stroke or Transient Ischemic Attack (PREVENT Trial): A Randomized Controlled Trial.Neurorehabilitation and neural repair · 2022Trial
- Reducing Hypertension in a Poststroke Black and Hispanic Home Care Population: Results of a Pragmatic Randomized Controlled Trial.American journal of hypertension · 2020Trial
- Long-term effects on survival after a 1-year multifactorial vascular risk factor intervention after stroke or TIA: secondary analysis of a randomized controlled trial, a 7-year follow-up study.Vascular health and risk management · 2019Trial
- Conformity with guideline-directed medical therapy and clinical outcomes in secondary cardiovascular prevention-results of a German claims data analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Article
- A Comparative Analysis of Patient Demographics and Referral Trends Pre- and Post-Intervention of the TIA Pathway: A Retrospective Observational Study.Health science reports · 2026Article
- Decanoic acid modulates cerebral metabolism and attenuates ischemic injury in a mouse model.Metabolic brain disease · 2026Article
- Article
- Obstetric and perinatal outcomes in women with cerebrovascular accident vs. transient ischemic attack: an evaluation of a population database.Archives of gynecology and obstetrics · 2024Article
- Cost Effectiveness of Endovascular Ultrasound Renal Denervation in Patients with Resistant Hypertension.PharmacoEconomics - open · 2024Article
- Comparing the EQ-5D-5L and stroke impact scale 2.0 in stroke patients: an analysis of measurement properties.Health and quality of life outcomes · 2024Article
- Cost-Effectiveness Analysis of Pharmacogenomics (PGx)-Based Warfarin, Apixaban, and Rivaroxaban Versus Standard Warfarin for the Management of Atrial Fibrillation in Ontario, Canada.PharmacoEconomics · 2024Article
- Evaluating Feasibility of a Secondary Stroke Prevention Program.Healthcare (Basel, Switzerland) · 2023Article
- Long-term risk of major adverse cardiovascular events following ischemic stroke or TIA.Scientific reports · 2023Article
- Blood pressure trajectory of inpatient stroke rehabilitation patients from the Determining Optimal Post-Stroke Exercise (DOSE) trial over the first 12 months post-stroke.Frontiers in neurology · 2023Article
- Addressing the diagnostic gap in hypertension through possible interventions and scale-up: A microsimulation study.PLoS medicine · 2022Article
- Association Between Inappropriately Dosed Anticoagulation Therapy With Stroke Severity and Outcomes in Patients With Atrial Fibrillation.Journal of the American Heart Association · 2022Article
- Risk Factors and Incidence of Acute Ischemic Stroke: A Comparative Study Between Young Adults and Older Adults.Cureus · 2021Article
- Admission and Readmission/Death Patterns in Hospitalized and Non-hospitalized First-Ever-in-a-Lifetime Stroke Patients During the First Year: A Population-Based Incidence Study.Frontiers in neurology · 2021Article
- Mediators, confounders and effectiveness of interventions for medication adherence after stroke.British journal of neuroscience nursing · 2020Article
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4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSecondary prevention after stroke and transient ischemic attack (TIA) has focused on high early risk of recurrence, but survivors of stroke can have substantial long-term morbidity and mortality. We quantified long-term morbidity and mortality for patients who had no early complications after stroke or TIA and community-based controls.
methodsThis longitudinal case-control study included all ambulatory or hospitalized patients with stroke or TIA (discharged from regional stroke centres in Ontario from 2003 to 2013) who survived for 90 days without recurrent stroke, myocardial infarction, all-cause admission to hospital, admission to an institution or death. Cases and controls were matched on age, sex and geographic location. The primary composite outcome was death, stroke, myocardial infarction, or admission to long-term or continuing care. We calculated 1-, 3- and 5-year rates of composite and individual outcomes and used cause-specific Cox regression to estimate long-term hazards for cases versus controls and for patients with stroke versus those with TIA.
resultsAmong patients who were initially stable after stroke or TIA (
interpretationPatients who survive stroke or TIA without early complications are typically discharged from secondary stroke prevention services. However, these patients remain at substantial long-term risk, particularly for recurrent stroke and admission to an institution. Novel approaches to prevention, potentially embedded in community or primary care, are required for long-term management of these initially stable but high-risk patients.
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