Evidence map›Paper›PMID 28739824›Full record

ArticleInfection and immunity2017

Epigenetic Mechanisms Regulate Innate Immunity against Uropathogenic and Commensal-Like Escherichia coli in the Surrogate Insect Model Galleria mellonella.

Miriam Heitmueller, André Billion, Ulrich Dobrindt, Andreas Vilcinskas, Krishnendu Mukherjee

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Epigenetic remodeling in insect immune memory.Frontiers in immunology · 2024
    Review
  7. The VirtuousAntibiotics (Basel, Switzerland) · 2023
    Review
  8. Repurposing HDAC inhibitors to enhance ribonuclease 4 and 7 expression and reduce urinary tract infection.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Epigenetic Molecular Mechanisms in Insects.Neotropical entomology · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Miriam HeitmuellerFraunhofer Institute for Molecular Biology and Applied Ecology, Department of Bioresources, Giessen, Germany.
André BillionFraunhofer Institute for Molecular Biology and Applied Ecology, Department of Bioresources, Giessen, Germany.
Ulrich DobrindtInstitute of Hygiene, University of Münster, Münster, Germany.ORCID http://orcid.org/0000-0001-9949-1898
Andreas VilcinskasInstitute for Insect Biotechnology, Justus-Liebig University of Giessen, Giessen, Germany andreas.vilcinskas@agrar.uni-giessen.de krishnendu.mukherjee@agrar.uni-giessen.de.
Krishnendu MukherjeeFraunhofer Institute for Molecular Biology and Applied Ecology, Department of Bioresources, Giessen, Germany andreas.vilcinskas@agrar.uni-giessen.de krishnendu.mukherjee@agrar.uni-giessen.de.
Fraunhofer Institute for Molecular Biology and Applied Ecology · DEJustus-Liebig-Universität Gießen · DEUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innate-immunity-related genes in humans are activated during urinary tract infections (UTIs) caused by pathogenic strains of

Indexed as

Epigenesis, GeneticAnimalsAntimicrobial Cationic PeptidesDNA, BacterialDNA MethylationEscherichia coliEscherichia coli ProteinsGene Expression ProfilingGene Expression RegulationHigh-Throughput Nucleotide SequencingImmunity, InnateLepidopteraPolymerase Chain ReactionToll-Like ReceptorsUropathogenic Escherichia coliVirulenceAntimicrobial Cationic PeptidesDNA, BacterialEscherichia coli ProteinsToll-Like ReceptorsVirulence Factorsantimicrobial peptidesasymptomatic bacteriuriaDNA methylationepigeneticsGalleria mellonellahistone acetylationinnate immunityToll-like receptorsurologyuropathogenic E. coli

Identifiers

PMID28739824
PMCPMC5607417
OpenAlexW2738999302

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.