Evidence map›Paper›PMID 28739805›Full record

ArticleThe Journal of biological chemistry2017

Functional insights into the mode of DNA and ligand binding of the TetR family regulator TylP from

Shamayeeta Ray, Anwesha Maitra, Anwesha Biswas, Santosh Panjikar, Jagannath Mondal, Ruchi Anand

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Shamayeeta RayFrom the Department of Chemistry, Indian Institute of Technology Bombay, Mumbai-400076, India.
Anwesha MaitraFrom the Department of Chemistry, Indian Institute of Technology Bombay, Mumbai-400076, India.
Anwesha BiswasFrom the Department of Chemistry, Indian Institute of Technology Bombay, Mumbai-400076, India.
Santosh Panjikarthe Department of Biochemistry and Molecular Biology, Monash University, Victoria 3800, Australia.
Jagannath Mondalthe Tata Institute of Fundamental Research (TIFR) Centre for Interdisciplinary Sciences, Hyderabad-500075, India.
Ruchi AnandFrom the Department of Chemistry, Indian Institute of Technology Bombay, Mumbai-400076, India, ruchi@chem.iitb.ac.in.ORCID 0000-0002-2045-3758
Indian Institute of Technology Bombay · INAustralian Synchrotron · AUTIFR Centre for Interdisciplinary Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tetracycline repressors (TetRs) modulate multidrug efflux pathways in several pathogenic bacteria. In

Indexed as

Models, MolecularAmino Acid SubstitutionApoproteinsBacterial ProteinsBinding SitesCircular DichroismCrystallography, X-RayElectrophoretic Mobility Shift AssayGene DeletionHydrogen BondingLigandsMolecular Docking SimulationMolecular Dynamics SimulationMutationPeptide FragmentsProtein ConformationApoproteinsBacterial ProteinsLigandsPeptide FragmentsRecombinant Fusion ProteinsSelenomethionineTrans-Activatorsactinobacteriabacterial metabolismC-terminal extensionDNA bindingDNA-binding proteinquorum sensingTetR family regulatortylosin regulationTylPX-ray crystallography

Identifiers

PMID28739805
PMCPMC5602390
OpenAlexW2738263720

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.