Evidence map›Paper›PMID 28739786›Full record

ArticleAntimicrobial agents and chemotherapy2017

Benzoxazoles, Phthalazinones, and Arylurea-Based Compounds with IMP Dehydrogenase-Independent Antibacterial Activity against Francisella tularensis.

Suresh Kumar Gorla, Yan Zhang, Meaghan M Rabideau, Aiping Qin, Shibin Chacko, Amanda L House, Corey R Johnson, Kavitha Mandapati, Hannah M Bernstein, Elizabeth S McKenney and 7 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Evaluation of Bronopol and Disulfiram as PotentialMolecules (Basel, Switzerland) · 2020
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Suresh Kumar GorlaDepartment of Biology, Brandeis University, Waltham, Massachusetts, USA.
Yan ZhangDepartment of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA.
Meaghan M RabideauDepartment of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA.
Aiping QinDepartment of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA.
Shibin ChackoDepartment of Biology, Brandeis University, Waltham, Massachusetts, USA.
Amanda L HouseDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, USA.
Corey R JohnsonDepartment of Chemistry, Brandeis University, Waltham, Massachusetts, USA.
Kavitha MandapatiDepartment of Biology, Brandeis University, Waltham, Massachusetts, USA.
Hannah M BernsteinDepartment of Biology, Brandeis University, Waltham, Massachusetts, USA.
Elizabeth S McKenneyDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, USA.
Helena BoshoffTuberculosis Research Section, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.
Minjia ZhangDepartment of Biology, Brandeis University, Waltham, Massachusetts, USA.
Ian J GlomskiDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, USA.
Joanna B GoldbergDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia, USA.
Gregory D CunyDepartment of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas, USA.
Barbara J MannDepartment of Medicine, Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, Virginia, USA.
Lizbeth HedstromDepartment of Biology, Brandeis University, Waltham, Massachusetts, USA hedstrom@brandeis.edu.
University of Virginia · USBrandeis University · USNational Institute of Allergy and Infectious Diseases · USUniversity of Houston · US

Funding

Development Of New Chemotherapeutics For TuberculosisZIAAI000693 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BARRY, CLIFTON · 2009 to 2025
$20.1M
IMPDH-targeted antibiotics for select agentsR01AI093459 · NIAID · BRANDEIS UNIVERSITY · PI HEDSTROM, LIZBETH K. · 2011 to 2015
$5.3M
NIAID NIH HHS R01 AI093459
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnti-Bacterial AgentsBenzoxazolesCell LineElectron Transport Complex IFrancisella tularensisHumansIMP DehydrogenaseMiceMicrobial Sensitivity TestsPhthalazinesStructure-Activity RelationshipTularemiaAnti-Bacterial AgentsBenzoxazolesElectron Transport Complex IIMP DehydrogenasePhthalazinescomplex IFrancisella tularensisIMP dehydrogenase

Identifiers

PMID28739786
PMCPMC5610529
OpenAlexW2738780198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.