Trial reportContemporary clinical trials2017
The women in steady exercise research (WISER) survivor trial: The innovative transdisciplinary design of a randomized controlled trial of exercise and weight-loss interventions among breast cancer survivors with lymphedema.
Trial report in Contemporary clinical trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01515124 (The Women In Steady Exercise Research), which is not on this map. Cited by 28 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Women In Steady Exercise Research (WISER) Survivor Trial & Cost of Illness and Cost Effectiveness of Alternative Management Strategies
Who cites it
28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- A meta-analysis of healthy lifestyle interventions addressing quality of life of cancer survivors in the post treatment phase.Journal of cancer survivorship : research and practice · 2025Pooled it
- Identifying the effective behaviour change techniques in nutrition and physical activity interventions for the treatment of overweight/obesity in post-treatment breast cancer survivors: a systematic review.Cancer causes & control : CCC · 2023Pooled it
- Body weight management in overweight and obese breast cancer survivors.The Cochrane database of systematic reviews · 2020Pooled it
- Resistance exercise and breast cancer-related lymphedema-a systematic review update and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Pooled it
- Exercise therapies for preventing or treating aromatase inhibitor-induced musculoskeletal symptoms in early breast cancer.The Cochrane database of systematic reviews · 2020Pooled it
- Evaluating the relationship between physical activity and quality of life in a racially diverse sample of breast cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Trial
- The effects of exercise and diet on oxidative stress and telomere length in breast cancer survivors.Breast cancer research and treatment · 2023Trial
- The effects of exercise and diet on sex steroids in breast cancer survivors.Endocrine-related cancer · 2022Trial
- Trial
- WISER Survivor Trial: Combined Effect of Exercise and Weight Loss Interventions on Insulin and Insulin Resistance in Breast Cancer Survivors.Nutrients · 2021Trial
- A randomized trial of exercise and diet on body composition in survivors of breast cancer with overweight or obesity.Breast cancer research and treatment · 2021Trial
- Preoperative physical activity patterns and postoperative outcomes in early-stage non-small cell lung cancer: a retrospective observational cohort study.Journal of thoracic disease · 2026Article
- Can Resistance Training Prevent Breast Cancer-Related Lymphedema? A Systematic Review with Meta-Analysis.Journal of clinical medicine · 2026Review
- Comprehensive Breast Cancer-Related Lymphedema Management Programs Addressing both Psychosocial and Physical Needs: A Scoping Review.The open journal of occupational therapy · 2025Article
- The Group-basEd Telehealth behavioral WEight Loss Program Among Breast Cancer Survivors: A Pilot and Feasibility Study.Obesity science & practice · 2024Article
- Identification of weight loss interventions for translation among endometrial cancer survivors: A RE-AIM analysis.Translational behavioral medicine · 2024Review
- Review
- Article
- The Effectiveness of Virtual Reality-Based Interventions in Rehabilitation Management of Breast Cancer Survivors: Systematic Review and Meta-analysis.JMIR serious games · 2022Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 8 institutions in 2 countries.
Funding
Abstract
introductionBreast cancer survivors face dual challenges: long term sequelae of treatment, and risk of recurrent disease. Obesity and a sedentary lifestyle complicate both challenges. The WISER Survivor trial assessed the effects of exercise and/or weight-loss on lymphedema, biomarkers of breast cancer recurrence, and quality of life. We report on the innovative transdisciplinary design of this trial and report attrition rates.
methodsThis one year trial randomized breast cancer survivors who had a BMI of ≥25kg/m RESULTS & DISCUSSION: 351 participants were randomized; 13 experienced breast cancer recurrence during the trial. Of the 338 participants without recurrence, 83% completed the trial. The WISER Survivor trial will show the effects of exercise and weight-loss on lymphedema outcomes, biomarkers of recurrence and quality of life. NCT ClinicalTrials.gov registration #: NCT01515124.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.