Evidence map›Paper›PMID 28738299›Full record

ArticleEnvironmental research2017

The impact of BMI on non-malignant respiratory symptoms and lung function in arsenic exposed adults of Northern Chile.

Anthony Nardone, Catterina Ferreccio, Johanna Acevedo, Wayne Enanoria, Alden Blair, Allan H Smith, John Balmes, Craig Steinmaus

Open access · bronzeAbstract read
In one paragraph

Article in Environmental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Toxic metal exposure as a possible risk factor for COVID-19 and other respiratory infectious diseases.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2020
    Pooled it
  2. Article
  3. Update of the risk assessment of inorganic arsenic in food.EFSA journal. European Food Safety Authority · 2024
    Article
  4. Review
  5. Article
  6. Mapping the Morbidity Risk Associated with Coal Mining in Queensland, Australia.International journal of environmental research and public health · 2022
    Article
  7. Article
  8. Arsenic and Obesity: a Review of Causation and Interaction.Current environmental health reports · 2020
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Anthony NardoneGlobal Health Sciences Program, University of California San Francisco, San Francisco, CA, USA.
Catterina FerreccioSchool of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile; Advanced Center for Chronic Diseases (ACCDiS), FONDAP, Santiago, Chile.
Johanna AcevedoSchool of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile; Advanced Center for Chronic Diseases (ACCDiS), FONDAP, Santiago, Chile.
Wayne EnanoriaDepartment of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA.
Alden BlairGlobal Health Sciences Program, University of California San Francisco, San Francisco, CA, USA.
Allan H SmithArsenic Health Effects Research Program, University of California Berkeley, School of Public Health, Berkeley, CA, USA.
John BalmesDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA; Division of Environmental Health Sciences, University of California Berkeley, School of Public Health, Berkeley, CA, USA.
Craig SteinmausArsenic Health Effects Research Program, University of California Berkeley, School of Public Health, Berkeley, CA, USA. Electronic address: craigs@berkeley.edu.
University of California, San Francisco · USAdvanced Center for Chronic Diseases · CLBerkeley Public Health Division · USUniversity of California, Berkeley · US

Funding

Training CoreP42ES004705 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI MCHALE, CLIONA · 1987 to 2025
$74.6M
Incident cancer studies in a unique arsenic-exposed area of ChileR01ES014032 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI STEINMAUS, CRAIG M · 2007 to 2018
$3.8M
In utero and childhood exposure to arsenic in water and lifelong lung diseaseR01ES017463 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI STEINMAUS, CRAIG M · 2009 to 2011
$1.3M
NIEHS NIH HHS P42 ES004705NIEHS NIH HHS R01 ES014032NIEHS NIH HHS R01 ES017463
6 · The paper itself

Abstract

backgroundElevated body mass index (BMI) and arsenic are both associated with cancer and with non-malignant lung disease. Using a unique exposure situation in Northern Chile with data on lifetime arsenic exposure, we previously identified the first evidence of an interaction between arsenic and BMI for the development of lung cancer.

objectivesWe examined whether there was an interaction between arsenic and BMI for the development of non-malignant lung disease.

methodsData on lifetime arsenic exposure, respiratory symptoms, spirometry, BMI, and smoking were collected from 751 participants from cities in Northern Chile with varying levels of arsenic water concentrations. Spirometry values and respiratory symptoms were compared across subjects in different categories of arsenic exposure and BMI.

resultsAdults with both a BMI above the 90th percentile (>33.9kg/m

conclusionsThis study provides preliminary evidence that BMI may increase the risk for arsenic-related non-malignant respiratory disease.

Indexed as

Body Mass IndexEnvironmental ExposureAdultArsenicChileFemaleHumansLung DiseasesMaleMiddle AgedPrevalenceRespiration DisordersRisk FactorsWater Pollutants, ChemicalArsenicWater Pollutants, ChemicalArsenicBody mass indexChileLung functionSpirometry

Identifiers

PMID28738299
PMCPMC5603214
OpenAlexW2736324064

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.