ArticleScience immunology2017
Resident memory T cells in the skin mediate durable immunity to melanoma.
Abstract read
In one paragraph
Article in Science immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 192 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
192citing papers in PubMed, 2 pooled it
11.7field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
192 citing papers in PubMed, 2 syntheses or guidelines pooled it, 271 citations in OpenAlex.
- Vitiligo-like Lesions as a Predictor of Response to Immunotherapy in Non-Small Cell Lung Cancer: Comprehensive Review and Case Series from a University Center.Current oncology (Toronto, Ont.) · 2024Pooled it
- Tissue-Resident Memory T Cells in Skin Diseases: A Systematic Review.International journal of molecular sciences · 2021Pooled it
- Greater extent of blood-tumor TCR repertoire overlap is associated with favorable clinical responses to PD-1 blockade.Cancer science · 2021Trial
- An orthotopic organoid-based model to study early CD8⁺ T cell dysfunction and immunotherapy response in colorectal cancer.Oncoimmunology · 2026Article
- Poliosis predicts durable response to immune-checkpoint blockade in metastatic melanoma: a multicenter cohort study.Journal for immunotherapy of cancer · 2026Article
- The initial melanoma T cell infiltrate is defined by tissue-resident programs restrained by regulatory T cells.Research square · 2026Article
- CD8MedComm · 2026Review
- Tumor-resident T cells and dendritic cells form an in situ archetype during immunotherapy response in melanoma.Nature communications · 2026Article
- Living rent free in your head: resident memory T cells.ImmunoHorizons · 2026Review
- Peripheral vaccination-induced brain-resident memory CD8+ T cells durably protect mice against intracranial malignancy.The Journal of clinical investigation · 2026Article
- The immunology of vitiligo.Nature reviews. Immunology · 2026Review
- Oral immunization withJournal for immunotherapy of cancer · 2026Article
- The CD8 immgenT framework as a universal reference of mouse CD8αβ T cell differentiation states.bioRxiv : the preprint server for biology · 2026Article
- Phenotypic Characterization and Prognostic Impact of CD103+ Tissue-Resident Memory T Cells in Diffuse Large B-cell Lymphoma.Cancer immunology research · 2026Article
- Mucosal immunity in cancer metastasis: roles, mechanisms, and therapeutic implications.Frontiers in immunology · 2026Review
- T-cell-targeted immunotherapy in neurofibromatosis type 2-related vestibular schwannoma: current evidence and future direction.Brain communications · 2026Review
- Tissue-resident exhausted and memory CD8Nature immunology · 2026Article
- Evolving role of CD8Frontiers in immunology · 2026Review
- Tissue-resident memory T cells in atopic dermatitis: mechanisms of residual inflammation, relapse, and therapeutic persistence.Frontiers in immunology · 2026Review
- Stem-like T cells: molecular regulation, functional diversity, and therapeutic implications across diseases.Journal of translational medicine · 2025Review
132 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Brian T MalikDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.ORCID http://orcid.org/0000-0002-9022-0044
Katelyn T ByrneDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
Jennifer L VellaDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.ORCID http://orcid.org/0000-0002-6190-8114
Peisheng ZhangDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
Tamer B ShabanehDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.ORCID http://orcid.org/0000-0001-7895-7134
Shannon M SteinbergDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
Aleksey K MolodtsovDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.ORCID http://orcid.org/0000-0002-4629-808X
Jacob S BowersDepartments of Microbiology and Immunology, and Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Christina V AngelesDepartment of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.
Chrystal M PaulosDepartments of Microbiology and Immunology, and Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Yina H HuangDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.ORCID http://orcid.org/0000-0002-0125-9351
Mary Jo TurkDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA. mary.jo.turk@dartmouth.edu.ORCID http://orcid.org/0000-0002-9612-8329
Dartmouth College · USMedical University of South Carolina · USDartmouth–Hitchcock Medical Center · US
Funding
Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3MTranslational Science Laboratory Shared ResourceP30CA138313 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Jian Ouyang · 2009 to 2026
$42.7MIMMUNOBIOLOGY OF MYELOID AND LYMPHOID CELLST32AI007363 · NIAID · DARTMOUTH COLLEGE · PI Claudia V Jakubzick · 1990 to 2026
$9.5MTRAINING PROGRAM FOR MEDICAL SCIENTISTST32GM008716 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DEMORE, NANCY · 1999 to 2024
$9.3MMolecular and Cellular Biology at DartmouthT32GM008704 · NIGMS · DARTMOUTH COLLEGE · PI COMPTON, DUANE A. · 1998 to 2018
$6.8MCenter for Molecular, Cellular, and Translational ImmunologyP30GM103415 · NIGMS · DARTMOUTH COLLEGE · PI GREEN, WILLIAM R · 2012 to 2015
$4.7MPIP3-INDEPENDENT REGULATION OF AKT1 ACTIVITY IN T CELLSR01AI089805 · NIAID · WASHINGTON UNIVERSITY · PI HUANG, YINA HSING · 2011 to 2021
$4.2MMechanisms of concomitant tumor immunity and autoimmunityR01CA120777 · NCI · DARTMOUTH COLLEGE · PI TURK, MARY JO · 2006 to 2016
$2.5MMechanisms of durable antitumor immunity via CD26hiCD4+ T cellsR01CA208514 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI PAULOS, CHRYSTAL MARY · 2016 to 2020
$1.7MCostimulatory mechanisms of antitumor Th17 cell immunityR01CA175061 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI PAULOS, CHRYSTAL MARY · 2013 to 2017
$1.5MImmunological manipulation of resistance to molecularly targeted inhibitorsR21CA209375 · NCI · DARTMOUTH COLLEGE · PI TURK, MARY JO · 2016 to 2017
$388kDefining and translating the properties that sustain the antitumor efficacy of Th17 cellsF30CA200272 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BOWERS, JACOB S · 2015 to 2018
$182kNCI NIH HHS F30 CA200272NCI NIH HHS P30 CA023108NCI NIH HHS P30 CA138313NCI NIH HHS R01 CA120777NCI NIH HHS R01 CA175061NCI NIH HHS R01 CA208514NCI NIH HHS R21 CA209375NIAID NIH HHS R01 AI089805NIAID NIH HHS T32 AI007363NIGMS NIH HHS P30 GM103415NIGMS NIH HHS T32 GM008704NIGMS NIH HHS T32 GM008716
Abstract
Tissue-resident memory T (T
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What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.