ArticleTransplantation2017
Toward Establishing Core Outcome Domains For Trials in Kidney Transplantation: Report of the Standardized Outcomes in Nephrology-Kidney Transplantation Consensus Workshops.
Article in Transplantation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06474273 (A Multicenter Randomized Controlled Trial to Treat Acute t Cell Mediated Rejection in Kidney and Kidney-pancreas Transplant Recipients), which is not on this map. Cited by 60 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Multicenter Randomized Controlled Trial to Treat Acute t Cell Mediated Rejection in Kidney and Kidney-pancreas Transplant Recipients
Who cites it
60 citing papers in PubMed, 5 syntheses or guidelines pooled it, 127 citations in OpenAlex.
- Antihypertensive treatment for kidney transplant recipients.The Cochrane database of systematic reviews · 2024Pooled it
- Guideline
- Interventions for improving health literacy in people with chronic kidney disease.The Cochrane database of systematic reviews · 2022Pooled it
- Mapping health-related quality of life after kidney transplantation by group comparisons: a systematic review.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021Pooled it
- Patient-reported outcome measures for life participation in peritoneal dialysis: a systematic review.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021Pooled it
- Occupational Priorities of People on Hemodialysis Who Participated in Energy Management Education.Canadian journal of occupational therapy. Revue canadienne d'ergotherapie · 2025Trial
- Using a measurement type-independent metric to compare patterns of determinants between patient-reported versus performance-based physical function in hemodialysis patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Trial
- Calcifediol supplementation in adults on hemodialysis: a randomized controlled trial.Journal of nephrology · 2022Trial
- Single-port robotic-assisted kidney transplantation: early benchmarks from a systematic review.International urology and nephrology · 2026Article
- Research evolution and evidence-generation priorities in robot-assisted living donor nephrectomy: a bibliometric and knowledge-mapping analysis.Journal of robotic surgery · 2026Article
- French Translation and Psychometric Evaluation of the Standardized Outcomes in Nephrology Life Participation Instrument Among Kidney Transplant Recipients.Kidney international reports · 2026Article
- Post-Transplant Hypertension in Kidney Recipients: Current Knowledge, Gaps and Future Directions.Journal of clinical medicine · 2026Review
- Patient-reported Outcome Measures in Solid Organ Transplant Recipients: Current use, Challenges, and Recommendations for Future use.Transplantation · 2026Review
- Prehabilitation interventions to support the postoperative recovery of adult kidney transplant candidates: a scoping review.BMC nephrology · 2026Article
- On the Importance of a Clear Definition of Time Horizon for Time-to-Event Dynamic Predictions: A Systematic Review and a Concrete Illustration in Kidney Transplantation.Clinical epidemiology · 2026Article
- Landscape of current practices and future perspectives in living donor kidney donation in Europe: proceedings of a pan-European symposium by the European kidney transplant association section of the European Society for Organ Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Establishing a core outcome measure for cancer in trials in kidney transplantation: a standardized outcomes in nephrology-kidney transplantation consensus workshop report.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Critically Important Cancer Outcomes to Report in Kidney Transplant Trials.Kidney international reports · 2025Article
- CARI Guideline: Evidence-Based Recommendations for Balanced Electrolyte Solutions to Improve Kidney Transplant Outcomes.Kidney international reports · 2025Article
- Assessing Social Participation Among Kidney Transplant Recipients Using PROMIS Computer Adaptive Testing.Kidney international reports · 2025Article
Corrections and comments
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Authors and funding
33 authors at 10 institutions in 8 countries.
Funding
Abstract
backgroundTreatment decisions in kidney transplantation requires patients and clinicians to weigh the benefits and harms of a broad range of medical and surgical interventions, but the heterogeneity and lack of patient-relevant outcomes across trials in transplantation makes these trade-offs uncertain, thus, the need for a core outcome set that reflects stakeholder priorities.
methodsWe convened 2 international Standardized Outcomes in Nephrology-Kidney Transplantation stakeholder consensus workshops in Boston (17 patients/caregivers; 52 health professionals) and Hong Kong (10 patients/caregivers; 45 health professionals). In facilitated breakout groups, participants discussed the development and implementation of core outcome domains for trials in kidney transplantation.
resultsSeven themes were identified. Reinforcing the paramount importance of graft outcomes encompassed the prevailing dread of dialysis, distilling the meaning of graft function, and acknowledging the terrifying and ambiguous terminology of rejection. Reflecting critical trade-offs between graft health and medical comorbidities was fundamental. Contextualizing mortality explained discrepancies in the prioritization of death among stakeholders-inevitability of death (patients), preventing premature death (clinicians), and ensuring safety (regulators). Imperative to capture patient-reported outcomes was driven by making explicit patient priorities, fulfilling regulatory requirements, and addressing life participation. Specificity to transplant; feasibility and pragmatism (long-term impacts and responsiveness to interventions); and recognizing gradients of severity within outcome domains were raised as considerations.
conclusionsStakeholders support the inclusion of graft health, mortality, cardiovascular disease, infection, cancer, and patient-reported outcomes (ie, life participation) in a core outcomes set. Addressing ambiguous terminology and feasibility is needed in establishing these core outcome domains for trials in kidney transplantation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.