Evidence map›Paper›PMID 28737174›Full record

ArticleNature communications2017

Inverted battery design as ion generator for interfacing with biosystems.

Chengwei Wang, Kun Kelvin Fu, Jiaqi Dai, Steven D Lacey, Yonggang Yao, Glenn Pastel, Lisha Xu, Jianhua Zhang, Liangbing Hu

Abstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Biopolymer Membranes for Osmotic Power Generation in Bionic Applications.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chengwei WangDepartment of Materials Science and Engineering, University of Maryland College Park, College Park, Maryland 20742, USA.
Kun Kelvin FuDepartment of Materials Science and Engineering, University of Maryland College Park, College Park, Maryland 20742, USA.
Jiaqi DaiDepartment of Materials Science and Engineering, University of Maryland College Park, College Park, Maryland 20742, USA.
Steven D LaceyDepartment of Materials Science and Engineering, University of Maryland College Park, College Park, Maryland 20742, USA.
Yonggang YaoDepartment of Materials Science and Engineering, University of Maryland College Park, College Park, Maryland 20742, USA.
Glenn PastelDepartment of Materials Science and Engineering, University of Maryland College Park, College Park, Maryland 20742, USA.
Lisha XuDepartment of Materials Science and Engineering, University of Maryland College Park, College Park, Maryland 20742, USA.
Jianhua ZhangMetabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
Liangbing HuDepartment of Materials Science and Engineering, University of Maryland College Park, College Park, Maryland 20742, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a lithium-ion battery, electrons are released from the anode and go through an external electronic circuit to power devices, while ions simultaneously transfer through internal ionic media to meet with electrons at the cathode. Inspired by the fundamental electrochemistry of the lithium-ion battery, we envision a cell that can generate a current of ions instead of electrons, so that ions can be used for potential applications in biosystems. Based on this concept, we report an 'electron battery' configuration in which ions travel through an external circuit to interact with the intended biosystem whereas electrons are transported internally. As a proof-of-concept, we demonstrate the application of the electron battery by stimulating a monolayer of cultured cells, which fluoresces a calcium ion wave at a controlled ionic current. Electron batteries with the capability to generate a tunable ionic current could pave the way towards precise ion-system control in a broad range of biological applications.

Indexed as

Electric Power SuppliesCells, CulturedElectrochemistryFluorescent DyesIonsIon TransportFluorescent DyesIons

Identifiers

PMID28737174
PMCPMC5527283

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.