Evidence map›Paper›PMID 28737102›Full record

ReviewJournal of comparative effectiveness research2017

Comparative effectiveness of rivaroxaban in the treatment of nonvalvular atrial fibrillation.

Faye L Norby, Alvaro Alonso

Open access · greenAbstract readReview
In one paragraph

Review in Journal of comparative effectiveness research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Faye L NorbyDivision of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454, USA.
Alvaro AlonsoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA 30322, USA.
Emory University · USUniversity of Minnesota · US

Funding

Comparative Effectiveness of Oral Anticoagulants in Atrial FibrillationR01HL122200 · NHLBI · UNIVERSITY OF MINNESOTA · PI ALONSO, ALVARO · 2015 to 2017
$1.2M
American Heart Association-American Stroke Association 16EIA26410001NHLBI NIH HHS R01 HL122200
6 · The paper itself

Abstract

Rivaroxaban is a direct oral anticoagulant (DOAC) approved for the prevention of stroke and systemic embolism in patients with nonvalvular atrial fibrillation, a common arrhythmia. In this review, we summarize the effectiveness of rivaroxaban versus warfarin and the DOACs dabigatran, apixaban and edoxaban. The primary focus is on primary evidence from clinical trials, indirect comparison studies and real-world studies. While there are gaps in the literature, the evidence thus far indicates that rivaroxaban is superior to warfarin and similar to dabigatran, apixaban and edoxaban for the prevention of stroke or systemic embolism in patients with nonvalvular atrial fibrillation, although rivaroxaban may be associated with an elevated bleeding risk compared with other DOACs.

Indexed as

Administration, OralAnticoagulantsAtrial FibrillationDabigatranDrug Administration ScheduleEpidemiologic MethodsFactor Xa InhibitorsFemaleHumansMalePyrazolesPyridinesPyridonesRivaroxabanStrokeThiazolesAnticoagulantsapixabanDabigatranedoxabanFactor Xa InhibitorsPyrazolesPyridinesPyridonesRivaroxabanThiazolesWarfarinanticoagulantsapixabancomparative effectivenessdabigatranedoxabanevidence-based medicinenonvalvular atrial fibrillationreal-world studiesrivaroxabanwarfarin

Identifiers

PMID28737102
PMCPMC5827778
OpenAlexW2738113730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.