Evidence map›Paper›PMID 28736562›Full record

ArticleCardiorenal medicine2017

Brain Natriuretic Peptide Is a Marker of Fluid Overload in Incident Hemodialysis Patients.

Charles Chazot, Margaux Rozes, Cyril Vo-Van, Patrik Deleaval, Jean-Marc Hurot, Christie Lorriaux, Brice Mayor, Eric Zaoui, Guillaume Jean

Abstract read
In one paragraph

Article in Cardiorenal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Brain natriuretic peptide reflects individual variation in hydration status in hemodialysis patients.Hemodialysis international. International Symposium on Home Hemodialysis · 2019
    Article
  10. Review
  11. Biomarkers in Cardiorenal Syndromes.BioMed research international · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Charles ChazotNephroCare Tassin-Charcot, Sainte-Foy-lès-Lyon, Nancy, France.
Margaux RozesNephroCare Tassin-Charcot, Sainte-Foy-lès-Lyon, Nancy, France.
Cyril Vo-VanNephroCare Tassin-Charcot, Sainte-Foy-lès-Lyon, Nancy, France.
Patrik DeleavalNephroCare Tassin-Charcot, Sainte-Foy-lès-Lyon, Nancy, France.
Jean-Marc HurotNephroCare Tassin-Charcot, Sainte-Foy-lès-Lyon, Nancy, France.
Christie LorriauxNephroCare Tassin-Charcot, Sainte-Foy-lès-Lyon, Nancy, France.
Brice MayorNephroCare Tassin-Charcot, Sainte-Foy-lès-Lyon, Nancy, France.
Eric ZaouiCerballiance, Sainte-Foy-lès-Lyon, France.
Guillaume JeanNephroCare Tassin-Charcot, Sainte-Foy-lès-Lyon, Nancy, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsBrain natriuretic peptide (BNP) is secreted by cardiomyocytes under stretch condition. High blood levels are associated with decreased patient survival in heart failure patients and in hemodialysis (HD) patients. We report the monthly BNP change in the first months of HD therapy in incident patients and its relationship with fluid removal and cardiac history (CH).

methodsAll patients starting HD therapy in our unit from May 2008 to December 2012 were retrospectively analyzed. Every month (M1 to M6), BNP was assessed before a midweek dialysis session. CH, monthly pre- and postdialysis blood pressure, and postdialysis body weight were collected.

resultsA total of 236 patients were included in the analysis. The median BNP at HD start was 593 (175-1,433) pg/mL, with a significant difference between CH- and CH+ patients (291 vs. 731 pg/mL,

conclusionsWe confirm that in incident HD patients, BNP level is related to fluid excess and cardiac status. The BNP decrease in the first months of HD therapy is related to fluid excess correction. BNP appears as an important tool to evaluate hydration status correction after HD onset.

Indexed as

Brain natriuretic peptideFluid overloadHemodialysisIncident patientsSurvival

Identifiers

PMID28736562
PMCPMC5511993

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.