Evidence map›Paper›PMID 28736527›Full record

ArticleFrontiers in physiology2017

Human COQ9 Rescues a

Cuiwen H He, Dylan S Black, Christopher M Allan, Brigitte Meunier, Shamima Rahman, Catherine F Clarke

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Characterization ofMetabolites · 2023
    Article
  2. Identification of novel coenzyme QThe Journal of biological chemistry · 2023
    Article
  3. Coenzyme Q10 levels increase with embryonic development in medaka.Journal of clinical biochemistry and nutrition · 2022
    Article
  4. Review
  5. Review
  6. Article
  7. Coenzyme QEssays in biochemistry · 2018
    Review
  8. Coenzyme QFrontiers in physiology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Cuiwen H HeDepartment of Chemistry and Biochemistry and the Molecular Biology Institute, University of California, Los AngelesLos Angeles, CA, United States.
Dylan S BlackDepartment of Chemistry and Biochemistry and the Molecular Biology Institute, University of California, Los AngelesLos Angeles, CA, United States.
Christopher M AllanDepartment of Chemistry and Biochemistry and the Molecular Biology Institute, University of California, Los AngelesLos Angeles, CA, United States.
Brigitte MeunierInstitut de Biologie Intégrative de la Cellule, CEA, Centre National de la Recherche Scientifique, UPSud, Paris-Saclay UniversityGif-sur-Yvette, France.
Shamima RahmanMetabolic Unit, Great Ormond Street Hospital for Children NHS Foundation TrustLondon, United Kingdom.
Catherine F ClarkeDepartment of Chemistry and Biochemistry and the Molecular Biology Institute, University of California, Los AngelesLos Angeles, CA, United States.
University of California, Los Angeles · USInstitut de Biologie Intégrative de la Cellule · FRUniversity College London · GB

Funding

CHEMISTRY BIOLOGY INTERFACE TRAINING PROGRAMT32GM008496 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAYNARD, HEATHER D · 1993 to 2019
$6.3M
LC-Triple Quadrupole Mass Spectrometer to Enhance LIfe Sciences ResearchS10RR024605 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LOO, JOSEPH A · 2007 to 2007
$424k
Medical Research Council G0200335NCRR NIH HHS S10 RR024605NIGMS NIH HHS T32 GM008496
6 · The paper itself

Abstract

Coq9 is required for the stability of a mitochondrial multi-subunit complex, termed the CoQ-synthome, and the deamination step of Q intermediates that derive from para-aminobenzoic acid (pABA) in yeast. In human, mutations in the

Indexed as

coenzyme Qhuman homologimmunoprecipitationmitochondrial metabolismSaccharomyces cerevisiaetemperature-sensitive mutant

Identifiers

PMID28736527
PMCPMC5500610
OpenAlexW2732287883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.