Evidence map›Paper›PMID 28736501›Full record

ReviewEuropean journal of organic chemistry2017

Design of Radioiodinated Pharmaceuticals: Structural Features Affecting Metabolic Stability towards in Vivo Deiodination.

Lorenzo Cavina, Dion van der Born, Peter H M Klaren, Martin C Feiters, Otto C Boerman, Floris P J T Rutjes

Open access · hybridAbstract readReview
In one paragraph

Review in European journal of organic chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 90 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Journal of extracellular vesicles · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. The [18F] F-PSMA Probe: Chemical Perspectives.Current medicinal chemistry · 2025
    Review
  10. Review
  11. RSC medicinal chemistry · 2024
    Article
  12. Article
  13. Synthesis and initialBioImpacts : BI · 2024
    Article
  14. Review
  15. Article
  16. Siderocalin fusion proteins enable a newRSC chemical biology · 2023
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Lorenzo CavinaInstitute of Molecules and Materials Faculty of Science Radboud University Heyendaalseweg 1356525 AJ Nijmegen Netherlands.ORCID 0000-0001-6700-1559
Dion van der BornFuture Chemistry Holding BV6525 EC Nijmegen Netherlands.ORCID 0000-0001-7381-1160
Peter H M KlarenDepartment of Animal Ecology & Physiology Institute of Water & Wetland Research Faculty of Science Radboud University POB 90106500 GL Nijmegen Netherlands.ORCID 0000-0001-7735-7196
Martin C FeitersInstitute of Molecules and Materials Faculty of Science Radboud University Heyendaalseweg 1356525 AJ Nijmegen Netherlands.ORCID 0000-0003-0130-835X
Otto C BoermanDepartment of Radiology & Nuclear Medicine Radboud University Medical Center 6500 HB Nijmegen the Netherlands.ORCID 0000-0001-6832-101X
Floris P J T RutjesInstitute of Molecules and Materials Faculty of Science Radboud University Heyendaalseweg 1356525 AJ Nijmegen Netherlands.ORCID 0000-0003-1538-3852
Radboud University Nijmegen · NLFuture Diagnostics (Netherlands) · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radioiodinated pharmaceuticals are convenient tracers for clinical and research investigations because of the relatively long half-lives of radioactive iodine isotopes (i.e.,

Indexed as

IodineIsotopic labelingMetabolismRadioiodinated pharmaceuticalsRadiolabeling

Identifiers

PMID28736501
PMCPMC5499721
OpenAlexW2609808249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.