Evidence map›Paper›PMID 28735556›Full record

ArticleBiological research for nursing2018

Quantitative Sensory Testing and Current Perception Threshold Testing in Patients With Chronic Pain Following Lower Extremity Fracture.

Mari A Griffioen, Joel D Greenspan, Meg Johantgen, Kathryn Von Rueden, Robert V O'Toole, Susan G Dorsey, Cynthia L Renn

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Biological research for nursing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mari A Griffioen1 School of Nursing, University of Delaware, Newark, DE, USA.
Joel D Greenspan2 School of Dentistry, University of Maryland, Baltimore, MD, USA.
Meg Johantgen3 School of Nursing, University of Maryland, Baltimore, MD, USA.
Kathryn Von Rueden3 School of Nursing, University of Maryland, Baltimore, MD, USA.
Robert V O'Toole4 School of Medicine, University of Maryland, Baltimore, MD, USA.
Susan G Dorsey3 School of Nursing, University of Maryland, Baltimore, MD, USA.
Cynthia L Renn3 School of Nursing, University of Maryland, Baltimore, MD, USA.
University of Maryland, Baltimore · USUniversity of Delaware · US

Funding

Efficacy of Acute Pain Management on Chronic Pain Following Lower Extremity TraumaF31NR014986 · NINR · UNIVERSITY OF MARYLAND BALTIMORE · PI GRIFFIOEN, MARI · 2014 to 2015
$49k
NINR NIH HHS F31 NR014986
6 · The paper itself

Abstract

backgroundChronic pain is a significant problem for patients with lower extremity injuries. While pain hypersensitivity has been identified in many chronic pain conditions, it is not known whether patients with chronic pain following lower extremity fracture report pain hypersensitivity in the injured leg. PURPOSE: To quantify and compare peripheral somatosensory function and sensory nerve activation thresholds in persons with chronic pain following lower extremity fractures with a cohort of persons with no history of lower extremity fractures.

methodThis was a cross-sectional study where quantitative sensory testing and current perception threshold testing were conducted on the injured and noninjured legs of cases and both legs of controls.

resultsA total of 14 cases and 28 controls participated in the study. Mean time since injury at the time of testing for cases was 22.3 (standard deviation = 12.1) months. The warmth detection threshold ( p = .024) and nerve activation thresholds at 2,000 Hz ( p < .001) and 250 Hz ( p = .002), respectively, were significantly higher in cases compared to controls.

conclusionThis study suggests that patients with chronic pain following lower extremity fractures may experience hypoesthesia in the injured leg, which contrasts with the finding of hyperesthesia previously observed in other chronic pain conditions but is in accord with patients with nerve injuries and surgeries. This is the first study to examine peripheral sensory nerve function at the site of injury in patients with chronic pain following lower extremity fractures using quantitative sensory testing and current perception threshold testing.

Indexed as

AdultChronic PainCohort StudiesCross-Sectional StudiesFemaleHumansLower ExtremityMaleMiddle AgedPain MeasurementPain ThresholdSensory Thresholdschronic paincurrent perception threshold testingquantitative sensory testingtraumatic lower extremity fracture

Identifiers

PMID28735556
PMCPMC5942497
OpenAlexW2790738541

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.