Evidence map›Paper›PMID 28735355›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018

A systematic review of dental disease management in cancer patients.

Catherine H L Hong, Shijia Hu, Thijs Haverman, Monique Stokman, Joel J Napeñas, Jacolien Bos-den Braber, Erich Gerber, Margot Geuke, Emmanouil Vardas, Tuomas Waltimo and 2 more

Open access · bronzeAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 111 citations in OpenAlex.

  1. Oral disease burden in children and adolescents scheduled for allogeneic haematopoietic stem cell transplantation: a multicentre study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
    Article
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  7. Dental Oncology: A Pressing Necessity for Comprehensive Cancer Care.Asian Pacific journal of cancer prevention : APJCP · 2025
    Review
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  14. The Implementation of an Integrated Oral Care Protocol for Pediatric Cancer Patients: a Qualitative Study.Journal of cancer education : the official journal of the American Association for Cancer Education · 2023
    Article
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  16. Review
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  18. Observational
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  20. Comparative study of royal jelly, propolis, and photobiomodulation therapies in 5-fluorouracil-related oral mucositis in rats.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 8 countries.

Catherine H L HongFaculty of Dentistry, National University of Singapore, Singapore, Singapore. denchhl@nus.edu.sg.ORCID http://orcid.org/0000-0003-0174-0652
Shijia HuFaculty of Dentistry, National University of Singapore, Singapore, Singapore.
Thijs HavermanDepartment of Oral Medicine, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University, Gustav Mahlerlaan 3004, 1081 LA, Amsterdam, The Netherlands.
Monique StokmanDepartment of Radiation Oncology and Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700 RB, Groningen, The Netherlands.
Joel J NapeñasDepartment of Oral Medicine, Carolinas HealthCare System, PO Box 32861, Charlotte, NC, 28232-2861, USA.
Jacolien Bos-den BraberDepartment of Oral Medicine, Carolinas HealthCare System, PO Box 32861, Charlotte, NC, 28232-2861, USA.
Erich GerberKaiser Franz Josef Spital, Institue for Radioonkologie, Vienna, Austria.
Margot GeukeDepartment of Oral and Maxillofacial Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Emmanouil VardasClinic of Hospital Dentistry, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
Tuomas WaltimoDepartment for Preventive Dentistry and Oral Microbiology, University Center for Dental Medicine Basel, University of Basel, Basel, Switzerland.
Siri Beier JensenDepartment of Dentistry and Oral Health, Aarhus University, Vennelyst Boulevard 9, DK-8000, Aarhus C, Denmark.
Deborah P SaundersDental Oncology Program, Health Sciences North, North East Cancer Center, 41 Ramsey Lake Road, Sudbury, ON, P3E 5J1, Canada.
Carolinas Healthcare System · USNational University of Singapore · SGAcademic Center for Dentistry Amsterdam · NLAmsterdam UMC Location University of Amsterdam · NLHealth Sciences North · CAKaiser-Franz-Josef-Spital · ATNational and Kapodistrian University of Athens · GRUniversity Medical Center Groningen · NLUniversity of Basel · CHUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis systematic review aims to update on the prevalence of odontogenic-related infections and the efficacy of dental strategies in preventing dental-related complications in cancer patients since the 2010 systematic review. REVIEW

methodA literature search was conducted in the databases MEDLINE/PubMed and EMBASE for articles published between 1 January 2009 and 30 June 2016. Each study was assessed by 2 reviewers and the body of evidence for each intervention was assigned an evidence level.

resultsAfter examination of the abstracts and full-text articles, 59 articles satisfied the inclusion criteria. The weighted prevalence of dental infections and pericoronitis during cancer therapy was 5.4 and 5.3%, respectively. The frequency of dental-related infections during intensive chemotherapy after complete, partial, and minimal pre-cancer dental evaluation/treatment protocols ranged from 0 to 4%. Protocols involving third molars extractions had the highest complications (40%).

conclusionsIn view of the low prevalence of infections and the potential for complications after third molar extractions, it is suggested that partial dental evaluation/treatment protocols prior to intensive chemotherapy; whereby minor caries (within dentin), asymptomatic third molars or asymptomatic teeth without excessive probing depth (<8 mm), mobility (mobility I or II) or with periapical lesions of <5 mm were observed; is a viable option when there is insufficient time for complete dental evaluation/treatment protocols. The use of chlorhexidine, fluoride mouth rinses as well as composite resin, resin-modified glass ionomer cement (GIC), and amalgam restorations over conventional GIC in post head and neck radiation patients who are compliant fluoride users is recommended.

Indexed as

Dental CareHumansNeoplasmsTooth DiseasesAnti-neoplastic agentsDental cariesHematopoietic stem cell transplantationPeriodontal disease

Identifiers

PMID28735355
OpenAlexW2736646821

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.