Trial reportTobacco control2018
Perceived nicotine content of reduced nicotine content cigarettes is a correlate of perceived health risks.
Trial report in Tobacco control, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Nicotine Reduction in Cigarettes: Literature Review and Gap Analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019Pooled it
- Independent and combined effects of very low nicotine cigarette messages and e-cigarette messages: a randomised clinical trial.Tobacco control · 2025Trial
- Acute effects of charcoal filters and package color on cigarette perceptions and use behaviors: Results from a randomized pilot study examining Natural American Spirit "Sky".Drug and alcohol dependence · 2024Trial
- Subjective experiences, contexts, and risk perceptions of very low nicotine content cigarettes and electronic cigarettes among people with depression and anxiety disorders who smoke.Drug and alcohol dependence · 2023Trial
- Effects of advertising features on smokers' and non-smokers' perceptions of a reduced nicotine cigarette modified risk tobacco product.Tobacco control · 2023Trial
- Educating the Public on the Health Risks of Very Low Nicotine Content Cigarettes: Results From a US-Based Convenience Sample.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022Trial
- Effects on Smoking Behavior of Switching Menthol Smokers to Non-menthol Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021Trial
- Article
- Assessing Tobacco Harm Perceptions Among Transgender and Nonbinary Adults: Results From a Community Informed State-Wide Survey.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Assessing the Impact of Messages About Reduced Nicotine Cigar Products Among People Who Use Little Cigars and Cigarillos: Insights From a Discrete Choice Experiment.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Young Adults' Attention to Reduced Exposure Claims in IQOS Advertising and Associations With Product Perceptions and Use Intentions.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Messaging about very low nicotine cigarettes (VLNCs) to influence policy attitudes, harm perceptions and smoking motivations: a discrete choice experiment.Tobacco control · 2024Article
- Reactions to Messages About a Nicotine Reduction Policy: A Focus Group Study Among People Who Use Little Cigars and Cigarillos.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Article
- Qualitative reactions to a low nicotine product standard for cigarettes from adolescents and young adults living in the United States who smoke.Preventive medicine reports · 2023Article
- "I Crave a Blunt, I Don't Crave a Cigarillo": A Focus Group Study on Perceptions of Nicotine and Addiction among US Adults Who Currently Smoke Little Cigars or Cigarillos.International journal of environmental research and public health · 2023Article
- A review of the evidence on cigarettes with reduced addictiveness potential.The International journal on drug policy · 2022Review
- Appeal, subjective effects, and relative reinforcing effects of JUUL that vary in flavor and nicotine content.Experimental and clinical psychopharmacology · 2021Article
- Reducing Nicotine Without Misleading the Public: Descriptions of Cigarette Nicotine Level and Accuracy of Perceptions About Nicotine Content, Addictiveness, and Risk.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019Article
- Misperceptions of Nicotine and Nicotine Reduction: The Importance of Public Education to Maximize the Benefits of a Nicotine Reduction Standard.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019Article
- Interest in Illicit Purchase of Cigarettes Under a Very Low Nicotine Content Product Standard.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 8 institutions in 2 countries.
Funding
Abstract
backgroundReducing cigarette nicotine content may reduce smoking. Studies suggest that smokers believe that nicotine plays a role in smoking-related morbidity. This may lead smokers to assume that reduced nicotine means reduced risk, and attenuate potential positive effects on smoking behaviour.
methodsData came from a multisite randomised trial in which smokers were assigned to use cigarettes varying in nicotine content for 6 weeks. We evaluated associations between perceived and actual nicotine content with perceived health risks using linear regression, and associations between perceived nicotine content and perceived health risks with smoking outcomes using linear and logistic regression.
findingsPerceived-not actual-nicotine content was associated with perceived health risks; compared with those perceiving very low nicotine, individuals who perceived low (
conclusionsAlthough the perception of reduced nicotine is associated with a reduction in perceived harm, it may not attenuate the anticipated beneficial effects on smoking behaviour. These findings have implications for potential product standards targeting nicotine and highlight the need to clarify the persistent harms of reduced nicotine combusted tobacco products.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.