Evidence map›Paper›PMID 28734512›Full record

ReviewPediatric clinics of North America2017

The Burden of Enteropathy and "Subclinical" Infections.

Elizabeth T Rogawski, Richard L Guerrant

Open access · greenAbstract readReview
In one paragraph

Review in Pediatric clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 46 citations in OpenAlex.

  1. Trial
  2. Review
  3. EnteroaggregativeEcoSal Plus · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Frontiers in public health · 2024
    Article
  10. Article
  11. Article
  12. Development of themSphere · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. Incidence of AsymptomaticLife (Basel, Switzerland) · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Acute Bacterial Gastroenteritis.Gastroenterology clinics of North America · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Elizabeth T RogawskiDepartment of Public Health Sciences, University of Virginia, PO Box 801379, Carter Harrison Research Building MR-6, 345 Crispell Drive, Room 2520, Charlottesville, VA 22908-1379, USA; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia, PO Box 801379, Carter Harrison Research Building MR-6, 345 Crispell Drive, Room 2520, Charlottesville, VA 22908-1379, USA. Electronic address: etr5m@virginia.edu.
Richard L GuerrantDivision of Infectious Diseases and International Health, Department of Medicine, University of Virginia, PO Box 801379, Carter Harrison Research Building MR-6, 345 Crispell Drive, Room 2520, Charlottesville, VA 22908-1379, USA.
University of Virginia · US

Funding

The Water and Health in Limpopo Innovations Fellowship ProgramD43TW009359 · FIC · UNIVERSITY OF VIRGINIA · PI GUERRANT, RICHARD L · 2012 to 2016
$1.7M
FIC NIH HHS D43 TW009359
6 · The paper itself

Abstract

Environmental enteropathy is a chronic condition of the small intestine associated with increased intestinal permeability, mucosal inflammation, malabsorption, and systemic inflammation. It is commonly accompanied by enteric infections and is misleadingly considered a subclinical disease. Potential effects of enteric infections and enteropathy on vaccine responses, child growth, cognitive development, and even later life obesity, diabetes, and metabolic syndrome are increasingly being recognized. Herein, we review the evolving challenges to defining environmental enteropathy and enteric infections, current evidence for the magnitude and determinants of its burden, new assessment tools, and relevant interventions.

Indexed as

Cost of IllnessBiomarkersChildEnvironmental ExposureHumansIntestinal DiseasesBiomarkersEnteric infectionsEnvironmental enteric dysfunctionEnvironmental enteropathyGrowth faltering

Identifiers

PMID28734512
PMCPMC5523808
OpenAlexW2736422767

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.