Evidence map›Paper›PMID 28734116›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2017

Preparing Platelet-Rich Plasma with Whole Blood Harvested Intraoperatively During Spinal Fusion.

Bin Shen, Zheng Zhang, Ning-Feng Zhou, Yu-Feng Huang, Yu-Jie Bao, De-Sheng Wu, Ya-Dong Zhang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Bin ShenDepartment of Spinal Surgery, East Hospital, Tongji University, School of Medicine, Shanghai, China (mainland).
Zheng ZhangDepartment of Orthopedic Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China (mainland).
Ning-Feng ZhouDepartment of Spinal Surgery, East Hospital, Tongji University, School of Medicine, Shanghai, China (mainland).
Yu-Feng HuangDepartment of Spinal Surgery, East Hospital, Tongji University, School of Medicine, Shanghai, China (mainland).
Yu-Jie BaoDepartment of Clinical Laboratory, East Hospital, Tongji University, School of Medicine, Shanghai, China (mainland).
De-Sheng WuDepartment of Spinal Surgery, East Hospital, Tongji University, School of Medicine, Shanghai, China (mainland).
Ya-Dong ZhangDepartment of Spinal Surgery, East Hospital, Tongji University, School of Medicine, Shanghai, China (mainland).
Shanghai East Hospital · CNJinzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND Platelet-rich plasma (PRP) has gained growing popularity in use in spinal fusion procedures in the last decade. Substantial intraoperative blood loss is frequently accompanied with spinal fusion, and it is unknown whether blood harvested intraoperatively qualifies for PRP preparation. MATERIAL AND METHODS Whole blood was harvested intraoperatively and venous blood was collected by venipuncture. Then, we investigated the platelet concentrations in whole blood and PRP, the concentration of growth factors in PRP, and the effects of PRP on the proliferation and viability of human bone marrow-derived mesenchymal stem cells (HBMSCs). RESULTS Our results revealed that intraoperatively harvested whole blood and whole blood collected by venipuncture were similar in platelet concentration. In addition, PRP formulations prepared from both kinds of whole blood were similar in concentration of platelet and growth factors. Additional analysis showed that the similar concentrations of growth factors resulted from the similar platelet concentrations of whole blood and PRP between the two groups. Moreover, these two kinds of PRP formulations had similar effects on promoting cell proliferation and enhancing cell viability. CONCLUSIONS Therefore, intraoperatively harvested whole blood may be a potential option for preparing PRP spinal fusion.

Indexed as

AdultAgedBlood PlateletsCell ProliferationCell SurvivalFemaleHumansIntercellular Signaling Peptides and ProteinsMaleMiddle AgedPlatelet-Rich PlasmaSpinal DiseasesSpinal FusionIntercellular Signaling Peptides and Proteins

Identifiers

PMID28734116
PMCPMC5536127
OpenAlexW2737931906

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.