Evidence map›Paper›PMID 28734088›Full record

Observational studyAddiction (Abingdon, England)2018

The stability of baseline-defined categories of alcohol consumption during the adult life-course: a 28-year prospective cohort study.

Craig S Knott, Steven Bell, Annie Britton

Abstract readObservational Study
In one paragraph

Observational study in Addiction (Abingdon, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  4. Article
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  6. Article
  7. Paternal and Maternal Problem Drinking and Lifetime Problem Drinking of Their Adult Children.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
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  14. Male alcohol consumption and fecundability.Human reproduction (Oxford, England) · 2020
    Article
  15. A Pilot Follow-Up Study of Older Alcohol-Dependent COGA Adults.Alcoholism, clinical and experimental research · 2019
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Craig S KnottResearch Department of Epidemiology and Public Health, University College London, London, UK.ORCID http://orcid.org/0000-0002-8593-6216
Steven BellResearch Department of Epidemiology and Public Health, University College London, London, UK.
Annie BrittonResearch Department of Epidemiology and Public Health, University College London, London, UK.ORCID http://orcid.org/0000-0002-6412-5430

Funding

Socio-economic status and heterogeneity in agingR01AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G, SINGH-MANOUX, ARCHANA · 1996 to 2013
$3.5M
Socioeconomic gradient in CHD in early old ageR01HL036310 · NHLBI · UNIVERSITY OF LONDON · PI KIVIMAKI, MIKA J, MARMOT, MICHAEL G · 1986 to 2012
$3.1M
DYNAMICS OF TRANSITION TO VENTRICULAR FIBRILLATIONF32HL008014 · NHLBI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SAXBERG, BO E · 1990 to 1990
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British Heart Foundation RG/08/014/24067British Heart Foundation RG/13/2/30098European Research Council 309337Medical Research Council G0902037Medical Research Council MR/L003120/1NHLBI NIH HHS R01 HL036310NIA NIH HHS R01 AG013196
6 · The paper itself

Abstract

BACKGROUND AND

aimsStudies that report the relationship between alcohol consumption and disease risk have predominantly operationalized drinking according to a single baseline measure. The resulting assumption of longitudinal stability may be simplistic and complicate interpretation of risk estimates. This study aims to describe changes to the volume of consumption during the adult life-course according to baseline categories of drinking.

designA prospective observational study.

settingUnited Kingdom.

participantsA cohort of British civil servants totalling 6838 men and 3372 women aged 34-55 years at baseline, followed for a mean 19.1 (standard deviation = 9.5) years. MEASUREMENTS: The volume of weekly alcohol consumption was estimated from data concerning the frequency and number of drinks consumed. Baseline categories were defined: non-current drinkers, infrequent drinkers, 0.1-50.0 g/week, 50.1-100.0 g/week, 100.1-150.0 g/week, 150.1-250.0 g/week and >250.0 g/week. For women, the highest category was defined as > 100.0 g/week. Baseline frequency was derived as 'daily or almost daily' and 'not daily or almost daily'. Trajectories were estimated within baseline categories using growth curve models.

findingsTrajectories differed between men and women, but were relatively stable within light-to-moderate categories of baseline consumption. Drinking was least stable within the highest categories of baseline consumption (men: > 250.0 g/week; women: > 100.0 g/week), declining by 47.0 [95% confidence interval (CI) = 40.7, 53.2] and 16.8 g/week (95% CI = 12.6, 21.0), respectively, per 10-year increase in age. These declines were not a consequence of sudden transitions to complete abstention. Rates of decline appear greatest in older age, with trajectories converging toward moderate volumes.

conclusionAmong UK civil servants, consumption within baseline drinking categories is generally stable during the life-course, except among heavier baseline drinkers, for whom intakes decline with increasing age. This shift does not appear to be driven by transitions to non-drinking. Cohorts of older people may be at particular risk of misclassifying former heavy drinkers as moderate consumers of alcohol.

Indexed as

AdultAlcohol DrinkingCohort StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesSex FactorsUnited KingdomAlcohol consumptiondrinkinglife courselongitudinal studymisclassification errortrajectories

Identifiers

PMID28734088
PMCPMC5725237

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.