ArticleThe journal of headache and pain2017
Perceived stress in patients with migraine: a case-control study.
Article in The journal of headache and pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 60 citations in OpenAlex.
- Prevalence and characteristics of cutaneous allodynia in probable migraine.Scientific reports · 2021Trial
- The Potential Pathway Among Self-Focused Attention, Rumination, Perceived Stress and Female Psychosomatic Symptoms.Behavioral sciences (Basel, Switzerland) · 2026Article
- The role and interaction of hypothalamic-related neurotransmitters in migraine.The journal of headache and pain · 2025Review
- Chronic Stress and Headaches: The Role of the HPA Axis and Autonomic Nervous System.Biomedicines · 2025Review
- Anxiety and depression among patients with migraine: A single-center cross-sectional study in Malaysia.PloS one · 2025Article
- Impact of migraine on changes in cardiovascular health profile among Hong Kong Chinese women: insights from the MECH-HK cohort study.The journal of headache and pain · 2024Article
- Right-to-left shunt-associated brain functional changes in migraine: evidences from a resting-state FMRI study.Frontiers in human neuroscience · 2024Article
- Network analysis of negative emotions in patients with episodic migraine: need for a multidisciplinary perspective.Frontiers in neurology · 2024Article
- Factors associated with stress-related symptoms among people with epilepsy in Ethiopia, a cross-sectional study.Frontiers in neurology · 2023Article
- Article
- Associations between migraine and possible risk factors in the Czech Republic.Frontiers in neurology · 2023Article
- Headache in Workers: A Matched Case-Control Study.European journal of investigation in health, psychology and education · 2022Article
- Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine.Brain : a journal of neurology · 2022Article
- Magnesium as an Important Factor in the Pathogenesis and Treatment of Migraine-From Theory to Practice.Nutrients · 2022Review
- Psychological Responses of Health Care Workers Are Strongly Associated With Pandemic Management.Frontiers in psychology · 2022Article
- Is there a causal relationship between stress and migraine? Current evidence and implications for management.The journal of headache and pain · 2021Review
- Chronic migraine in the first COVID-19 lockdown: the impact of sleep, remote working, and other life/psychological changes.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Impact of the COVID-19 pandemic on migraine in Japan: a multicentre cross-sectional study.The journal of headache and pain · 2021Article
- Article
- A novel, injury-free rodent model of vulnerability for assessment of acute and preventive therapies reveals temporal contributions of CGRP-receptor activation in migraine-like pain.Cephalalgia : an international journal of headache · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPerceived stress is the most common trigger for migraine. The objective of this study was to examine the clinical significance of perceived stress in migraine patients.
methodsThis is a case-control study. Consecutive migraine patients who visited a tertiary care hospital were enrolled for this study. They completed self-reported questionnaires including Perceived Stress Scale (PSS), 12-item Allodynia Symptom Checklist (ASC-12), Migraine Disability Assessment Scale (MIDAS), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), Epworth Sleepiness Scale (ESS), Insomnia Severity Index (ISI), and Migraine-Specific Quality of Life Questionnaire (MSQ). Degree of perceived stress in migraine patients was measured and compared to that in healthy controls. Predictors for perceived stress and their impact on quality of life (QOL) of migraine patients were also determined.
resultsA total of 227 migraine patients were eligible for this study, including 103 (45.4%) who had chronic migraine (CM). Mean PSS score was significantly (p < 0.05) higher in CM patients than that in controls after adjusting for education, depression, and anxiety. Although several factors were associated with PSS score, major predictors for PSS were GAD-7 score (β = 0.358, p < 0.001), PHQ-9 score (β = 0.304, p < 0.001), ISI score (β = 0.154, p = 0.005), and CM (β = -0.104, p = 0.027). There was an inverse relationship between PSS scores and three-dimensional scores of MSQ (p < 0.001).
conclusionsChronic migraine is a critical factor for perceived stress. Perceived stress affects QOL of migraine patients.
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