Evidence map›Paper›PMID 28733927›Full record

ArticleEuropean journal of nutrition2018

Nut intake and 5-year changes in body weight and obesity risk in adults: results from the EPIC-PANACEA study.

Heinz Freisling, Hwayoung Noh, Nadia Slimani, Véronique Chajès, Anne M May, Petra H Peeters, Elisabete Weiderpass, Amanda J Cross, Guri Skeie, Mazda Jenab and 36 more

Abstract read
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In one paragraph

Article in European journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

46 authors.

Heinz FreislingNutritional Methodology and Biostatistics Group, Section of Nutrition and Metabolism, International Agency for Research on Cancer (IARC-WHO), 150, Cours Albert Thomas, 69372, Lyon Cedex 08, France. freislingh@iarc.fr.
Hwayoung NohNutritional Methodology and Biostatistics Group, Section of Nutrition and Metabolism, International Agency for Research on Cancer (IARC-WHO), 150, Cours Albert Thomas, 69372, Lyon Cedex 08, France.
Nadia SlimaniNutritional Epidemiology Group, Section of Nutrition and Metabolism, International Agency for Research On Cancer (IARC-WHO), Lyon, France.
Véronique ChajèsNutritional Epidemiology Group, Section of Nutrition and Metabolism, International Agency for Research On Cancer (IARC-WHO), Lyon, France.
Anne M MayJulius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands.
Petra H PeetersJulius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands.
Elisabete WeiderpassDepartment of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.
Amanda J CrossDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Guri SkeieDepartment of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.
Mazda JenabNutritional Epidemiology Group, Section of Nutrition and Metabolism, International Agency for Research On Cancer (IARC-WHO), Lyon, France.
Francesca R ManciniInserm U1018, Gustave Roussy Institute, CESP, Villejuif, France.
Marie-Christine Boutron-RuaultInserm U1018, Gustave Roussy Institute, CESP, Villejuif, France.
Guy FagherazziInserm U1018, Gustave Roussy Institute, CESP, Villejuif, France.
Verena A KatzkeDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Tilman KühnDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Annika SteffenDepartment of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.
Heiner BoeingDepartment of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.
Anne TjønnelandDanish Cancer Society Research Center, Copenhagen, Denmark.
Cecilie KyrøDanish Cancer Society Research Center, Copenhagen, Denmark.
Camilla P HansenDepartment of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark.
Kim OvervadDepartment of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark.
Eric J DuellUnit of Nutrition and Cancer, IDIBELL, Catalan Institute of Oncology, Barcelona, Spain.
Daniel Redondo-SánchezEscuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain.
Pilar AmianoCIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Carmen NavarroCIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Aurelio BarricarteCIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Aurora Perez-CornagoCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Konstantinos K TsilidisDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Dagfinn AuneDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Heather WardDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Antonia TrichopoulouHellenic Health Foundation, Athens, Greece.
Androniki NaskaHellenic Health Foundation, Athens, Greece.
Philippos OrfanosHellenic Health Foundation, Athens, Greece.
Giovanna MasalaCancer Risk Factors and Life-Style Epidemiology Unit, Cancer Research and Prevention Institute, ISPO, Florence, Italy.
Claudia AgnoliEpidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Franco BerrinoEpidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Rosario TuminoCancer Registry and Histopathology Unit, "Civic-M.P.Arezzo" Hospital, ASP Ragusa, Ragusa, Italy.
Carlotta SacerdoteUnit of Cancer Epidemiology, Città della Salute e della Scienza University-Hospital and Center for Cancer Prevention (CPO), Turin, Italy.
Amalia MattielloDipartimento di Medicina Clinica E Chirurgia, Federico II University, Naples, Italy.
H Bas Bueno-de-MesquitaDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.
Ulrika EricsonDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Emily SonestedtDepartment of Clinical Sciences Malmö, Lund University, Malmö, Sweden.
Anna WinkvistDepartment of Internal Medicine and Clinical Nutrition, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Tonje BraatenDepartment of Community Medicine, Faculty of Health Sciences, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.
Isabelle RomieuNutritional Epidemiology Group, Section of Nutrition and Metabolism, International Agency for Research On Cancer (IARC-WHO), Lyon, France.
Joan SabatéCenter for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, USA.

Funding

Cancer Research UK 14136Cancer Research UK 16491Medical Research Council MR/M012190/1World Health Organization 001
6 · The paper itself

Abstract

purposeThere is inconsistent evidence regarding the relationship between higher intake of nuts, being an energy-dense food, and weight gain. We investigated the relationship between nut intake and changes in weight over 5 years.

methodsThis study includes 373,293 men and women, 25-70 years old, recruited between 1992 and 2000 from 10 European countries in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Habitual intake of nuts including peanuts, together defined as nut intake, was estimated from country-specific validated dietary questionnaires. Body weight was measured at recruitment and self-reported 5 years later. The association between nut intake and body weight change was estimated using multilevel mixed linear regression models with center/country as random effect and nut intake and relevant confounders as fixed effects. The relative risk (RR) of becoming overweight or obese after 5 years was investigated using multivariate Poisson regressions stratified according to baseline body mass index (BMI).

resultsOn average, study participants gained 2.1 kg (SD 5.0 kg) over 5 years. Compared to non-consumers, subjects in the highest quartile of nut intake had less weight gain over 5 years (-0.07 kg; 95% CI -0.12 to -0.02) (P trend = 0.025) and had 5% lower risk of becoming overweight (RR 0.95; 95% CI 0.92-0.98) or obese (RR 0.95; 95% CI 0.90-0.99) (both P trend <0.008).

conclusionsHigher intake of nuts is associated with reduced weight gain and a lower risk of becoming overweight or obese.

Indexed as

Body Mass IndexBody WeightNutsAdultAgedDietEnergy IntakeEuropeFemaleHumansMaleMiddle AgedObesityProspective StudiesRisk FactorsSurveys and QuestionnairesAdultsEnergy balanceEuropeNut intakeObesityWeight gain

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.