ArticlePsychopharmacology2017
Individual and combined effects of cannabis and tobacco on drug reward processing in non-dependent users.
Article in Psychopharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Experimental manipulations of behavioral economic demand for addictive commodities: a meta-analysis.Addiction (Abingdon, England) · 2020Pooled it
- Sensitivity of hypothetical purchase task indices when studying substance use: A systematic literature review.Preventive medicine · 2019Pooled it
- Co-use of cannabis and tobacco in the same occasion: Acute effects. A systematic review.Psychopharmacology · 2026Review
- [Cannabinoid content in seized hashish joints from Castilla y León (Spain)].Anales del sistema sanitario de Navarra · 2025Article
- Naturalistic substance use before/during MTurk research participation is associated with increased substance demand and craving.Experimental and clinical psychopharmacology · 2025Article
- Acute Stress Effect on Delay Discounting and Cannabis Demand Among Individuals Endorsing High-Frequency Cannabis Use.Cannabis (Albuquerque, N.M.) · 2025Article
- Applying a behavioral economic approach to understanding smoking processes: The indirect effect of past quit experiences.Drug and alcohol dependence · 2024Article
- Utility of a brief measure of cannabis demand: Day-level associations with cannabis use.Drug and alcohol dependence · 2024Article
- Tobacco, Alcohol, and Drug Use Among Young Adults with Serious Mental Illness.Community mental health journal · 2024Article
- Clinical Variables and Peripheral Biomarkers Associated with Substance-Induced Psychotic Disorder: Differences Related to Alcohol, Cannabis, and Psychostimulant Abuse.Journal of personalized medicine · 2024Article
- Exponentiated model of drug demand is preferred over exponential models in people with daily/near daily cannabis use.Experimental and clinical psychopharmacology · 2023Article
- Can I see some ID? Examining validity of the marijuana purchase task among late adolescent cannabis users.Experimental and clinical psychopharmacology · 2023Article
- Characteristics that influence purchase choice for cannabis products: a systematic review.Journal of cannabis research · 2022Review
- Using an Optimized Marijuana Purchase Task to Examine Cannabis Demand in Relation to Cannabis Misuse in Heavy Drinking Emerging Adults.Journal of studies on alcohol and drugs · 2021Article
- Unraveling the role of cigarette use in neural cannabis cue reactivity in heavy cannabis users.Addiction biology · 2021Article
- Perceived reward from using cigarettes with alcohol or cannabis and concurrent use: A smartphone-based daily diary study.Addictive behaviors · 2021Article
- Behavioral economic measurement of cigarette demand: A descriptive review of published approaches to the cigarette purchase task.Experimental and clinical psychopharmacology · 2020Review
- Measuring the temporal association between cannabis and tobacco use among Co-using young adults using ecological momentary assessment.Addictive behaviors · 2020Article
- Assessing Cannabis Demand: A Comprehensive Review of the Marijuana Purchase Task.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2020Review
- Neuronal nicotinic acetylcholine receptors mediate ∆Addiction biology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleCannabis and tobacco are often smoked simultaneously in joints, and this practice may increase the risks of developing tobacco and/or cannabis use disorders. Currently, there is no human experimental research on how these drugs interact on addiction-related measures.
objectivesThis study aimed to investigate how cannabis and tobacco, each alone and combined together in joints, affected individuals' demand for cannabis puffs and cigarettes, explicit liking of drug and non-drug-related stimuli and craving.
methodA double-blind, 2 (active cannabis, placebo cannabis) × 2 (active tobacco, placebo tobacco) crossover design was used with 24 non-dependent cannabis and tobacco smokers. They completed a pleasantness rating task (PRT), a marijuana purchase task (MPT) and a cigarette purchase task (CPT) alongside measures of craving pre- and post-drug administration.
resultsRelative to placebo cannabis, active cannabis reduced liking of cannabis-associated stimuli and increased response time to all stimuli except cigarette-related stimuli. Relative to placebo cannabis, active cannabis decreased demand for cannabis puffs (trends for breakpoint and elasticity) and cigarettes (breakpoint, P
conclusionsAcutely, cannabis reduced liking of cannabis-related stimuli and demand for cannabis itself. Acute cannabis also reduced demand for cigarettes on the CPT. Acute tobacco administration did not affect demand or pleasantness ratings for cigarettes themselves or cannabis. In non-dependent cannabis and tobacco co-users, tobacco did not influence the rewarding effects of cannabis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.