Evidence map›Paper›PMID 28733677›Full record

ArticleScientific reports2017

Inductively powered wireless pacing via a miniature pacemaker and remote stimulation control system.

Parinaz Abiri, Ahmad Abiri, René R Sevag Packard, Yichen Ding, Alireza Yousefi, Jianguo Ma, Malcolm Bersohn, Kim-Lien Nguyen, Dejan Markovic, Shervin Moloudi and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Remote monitoring of leadless pacemakers using a novel conductive telemetry communication method.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Observational
  2. Article
  3. Article
  4. [Development of a flexible embedded neurostimulator for animal robots].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. A Multi-Dimensional Analysis of a Novel Approach for Wireless Stimulation.IEEE transactions on bio-medical engineering · 2020
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Parinaz AbiriDepartment of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA.
Ahmad AbiriDepartment of Bioengineering, School of Engineering and Applied Sciences, UCLA, Los Angeles, CA, 90095, USA.
René R Sevag PackardDepartment of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA.
Yichen DingDepartment of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA.ORCID 0000-0002-6242-3506
Alireza YousefiDepartment of Electrical Engineering, School of Engineering and Applied Sciences, UCLA, Los Angeles, CA, 90095, USA.
Jianguo MaDepartment of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA.
Malcolm BersohnVA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd, Los Angeles, CA, 90073, USA.
Kim-Lien NguyenVA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd, Los Angeles, CA, 90073, USA.
Dejan MarkovicDepartment of Electrical Engineering, School of Engineering and Applied Sciences, UCLA, Los Angeles, CA, 90095, USA.
Shervin MoloudiDepartment of Electrical Engineering, School of Engineering and Applied Sciences, UCLA, Los Angeles, CA, 90095, USA.
Tzung K HsiaiDepartment of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, 90095, USA. THsiai@mednet.ucla.edu.

Funding

UCLA-Caltech Medical Scientist Training ProgramT32GM008042 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI AJIJOLA, OLUJIMI A, DAWSON, DAVID WAYNE · 1985 to 2023
$29.9M
Linking Spatial Variations Shear Stress-Oxidative StressR01HL083015 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HSIAI, TZUNG K · 2006 to 2015
$3.9M
Shear Stress and Light-Sheets to Study Cardiac TrabeculationR01HL129727 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HSIAI, TZUNG K, MARSDEN, ALISON L · 2015 to 2024
$3.5M
Electronica Impedance to Access Metabolically Active PlaqueR01HL118650 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HSIAI, TZUNG K · 2014 to 2022
$3.3M
Micro-Sensors to Study Electrical and Mechanical Coupling of Injured MyocardiumR01HL111437 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HSIAI, TZUNG K, XU, XIAOLEI · 2012 to 2020
$3.1M
NHLBI NIH HHS R01 HL083015NHLBI NIH HHS R01 HL111437NHLBI NIH HHS R01 HL118650NHLBI NIH HHS R01 HL129727
6 · The paper itself

Abstract

Pacemakers have existed for decades as a means to restore cardiac electrical rhythms. However, lead-related complications have remained a clinical challenge. While market-released leadless devices have addressed some of the issues, their pacer-integrated batteries cause new health risks and functional limitations. Inductive power transfer enables wireless powering of bioelectronic devices; however, Specific Absorption Rate and size limitations reduce power efficiency for biomedical applications. We designed a remote-controlled system in which power requirements were significantly reduced via intermittent power transfer to control stimulation intervals. In parallel, the cardiac component was miniaturized to facilitate intravascular deployment into the anterior cardiac vein. Given size constraints, efficiency was optimal via a circular receiver coil wrapped into a half-cylinder with a meandering tail. The pacemaker was epicardially tested in a euthanized pig at 60 beats per minute, 2 V amplitude, and 1 ms pulse width, restoring mean arterial pressure from 0 to 37 mmHg. Power consumption was 1 mW at a range of > 3 cm with no misalignment and at 2 cm with 45° displacement misalignment, 45° x-axis angular misalignment, or 45° y-axis angular misalignment. Thus, we demonstrated a remote-controlled miniaturized pacing system with low power consumption, thereby providing a basis for the next generation of wireless implantable devices.

Indexed as

Pacemaker, ArtificialAnimalsElectric Power SuppliesEquipment DesignHumansMiniaturizationSwineWireless Technology

Identifiers

PMID28733677
PMCPMC5522478

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.