Evidence map›Paper›PMID 28733486›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

α-Toxin Regulates Local Granulocyte Expansion from Hematopoietic Stem and Progenitor Cells in

Patrick C Falahee, Leif S Anderson, Mack B Reynolds, Mauricio Pirir, Bridget E McLaughlin, Carly A Dillen, Ambrose L Cheung, Lloyd S Miller, Scott I Simon

Open access · hybridAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Patrick C FalaheeDepartment of Biomedical Engineering, University of California, Davis, Davis, CA 95616.ORCID 0000-0002-3704-5902
Leif S AndersonDepartment of Biomedical Engineering, University of California, Davis, Davis, CA 95616.ORCID 0000-0002-0721-7523
Mack B ReynoldsDepartment of Biomedical Engineering, University of California, Davis, Davis, CA 95616.ORCID 0000-0002-8445-3749
Mauricio PirirDepartment of Biomedical Engineering, University of California, Davis, Davis, CA 95616.ORCID 0000-0003-0726-9232
Bridget E McLaughlinComprehensive Cancer Center Flow Cytometry Shared Resource, University of California, Davis, Davis, CA 95616.ORCID 0000-0001-5801-3996
Carly A DillenDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231; and.
Ambrose L CheungDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755.
Lloyd S MillerDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231; and.
Scott I SimonDepartment of Biomedical Engineering, University of California, Davis, Davis, CA 95616; sisimon@ucdavis.edu.ORCID 0000-0003-1186-6611
University of California, Davis · USJohns Hopkins University · USDartmouth College · US

Funding

Outside-in Mechanotransduced Inflammatory TargetsR01AI047294 · NIAID · UNIVERSITY OF CALIFORNIA DAVIS · PI SIMON, SCOTT IRWIN · 1999 to 2021
$7.0M
Predoctoral Training in Pharmacological SciencesT32GM099608 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HELL, JOHANNES W · 2012 to 2021
$2.2M
Engineering the innate immune response to Staphaureus infectionR01AI129302 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEACH, J. KENT, SIMON, SCOTT IRWIN · 2017 to 2021
$1.9M
STAT3-mediated immunity to Staphylococcus aureus in skinR01AR069502 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI ARCHER, NATHAN K. · 2016 to 2020
$1.8M
Engineering the immune response for improved resolution of Staphylococcus infectiR56AI103687 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SIMON, SCOTT IRWIN · 2013 to 2013
$371k
NIAID NIH HHS R01 AI047294NIAID NIH HHS R01 AI129302NIAID NIH HHS R56 AI103687NIAMS NIH HHS R01 AR069502NIGMS NIH HHS T32 GM099608
6 · The paper itself

Abstract

The immune response to

Indexed as

AnimalsBacterial LoadBacterial ToxinsCell DifferentiationCell ProliferationGranulocytesHematopoietic Stem CellsHemolysin ProteinsImmunomodulationMiceMice, Inbred C57BLMice, KnockoutMutationMyeloid Differentiation Factor 88Receptors, Interleukin-1Signal TransductionBacterial ToxinsHemolysin ProteinsMyd88 protein, mouseMyeloid Differentiation Factor 88Receptors, Interleukin-1staphylococcal alpha-toxinTlr2 protein, mouseToll-Like Receptor 2Virulence Factors

Identifiers

PMID28733486
PMCPMC5568467
OpenAlexW2738468345

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.