Evidence map›Paper›PMID 28733471›Full record

ArticleScience immunology2017

Jiani N Chai, Yangqing Peng, Sunaina Rengarajan, Benjamin D Solomon, Teresa L Ai, Zeli Shen, Justin S A Perry, Kathryn A Knoop, Takeshi Tanoue, Seiko Narushima and 8 more

Abstract read
In one paragraph

Article in Science immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Guardians within: Cross-talk between the gut microbiome and host immune system.World journal of gastrointestinal pathophysiology · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Host-pathobiont interactions in Crohn's disease.Nature reviews. Gastroenterology & hepatology · 2025
    Review
  16. Food science & nutrition · 2025
    Article
  17. Review
  18. Article
  19. Review
  20. Microbiology spectrum · 2025
    Article

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Jiani N ChaiDivision of Rheumatology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID http://orcid.org/0000-0003-2560-8218
Yangqing PengDivision of Rheumatology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID http://orcid.org/0000-0002-2394-3437
Sunaina RengarajanDivision of Rheumatology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Benjamin D SolomonDivision of Rheumatology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID http://orcid.org/0000-0003-1009-7312
Teresa L AiDivision of Rheumatology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID http://orcid.org/0000-0001-8376-9285
Zeli ShenDivision of Comparative Medicine, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Justin S A PerryDivision of Rheumatology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Kathryn A KnoopDivision of Gastroenterology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Takeshi TanoueRIKEN Center for Integrative Medical Sciences, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.
Seiko NarushimaRIKEN Center for Integrative Medical Sciences, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.
Kenya HondaRIKEN Center for Integrative Medical Sciences, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.
Charles O ElsonDivision of Gastroenterology and Hepatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Rodney D NewberryDivision of Gastroenterology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Thaddeus S StappenbeckDepartment of Pathology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Andrew L KauCenter for Women's Infectious Disease Research and Division of Allergy and Immunology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Daniel A PetersonEli Lilly and Co., Indianapolis, IN 46285, USA.
James G FoxDivision of Comparative Medicine, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Chyi-Song HsiehDivision of Rheumatology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. chsieh@wustl.edu.ORCID http://orcid.org/0000-0001-5976-9250

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
Washington University DDRCC Supplemental Equipment RequestP30DK052574 · NIDDK · WASHINGTON UNIVERSITY · PI Nicholas O. Davidson · 2000 to 2026
$30.8M
TOXICOLOGY CORE UNITP30ES002109 · NIEHS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LEVINE, STUART S · 1985 to 2020
$25.6M
UNIQUE ROLES OF ANTIGEN PRESENTING CELLS ON T CELL TOLERANCE AND AUTOIMMUNITYR01AI079187 · NIAID · WASHINGTON UNIVERSITY · PI HSIEH, CHYI S · 2008 to 2021
$5.8M
GOBLET CELLS IN INTESTINAL IMMUNE HOMEOSTATSISR01DK097317 · NIDDK · WASHINGTON UNIVERSITY · PI NEWBERRY, RODNEY D · 2012 to 2025
$5.6M
Biomedical Research Training for Veterinary ScientistsT32OD010978 · OD · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI FOX, JAMES G · 2012 to 2017
$2.2M
ANALYSIS OF BACTERIAL-SPECIFIC COLONIC ITREG CELLS IN IMMUNE-MEDIATED COLITISR01DK094995 · NIDDK · WASHINGTON UNIVERSITY · PI HSIEH, CHYI S · 2013 to 2016
$1.3M
THE MICROBIOTA AND MUCOSAL IMMUNE RESPONSES IN THE DEVELOPMENT OF ASTHMAK08AI113184 · NIAID · WASHINGTON UNIVERSITY · PI KAU, ANDREW LEON · 2015 to 2019
$792k
GUT INFLUENCES ON IMMUNE DEVELOPMENT IN EARLY LIFEK01DK109006 · NIDDK · WASHINGTON UNIVERSITY · PI KNOOP, KATHRYN A · 2016 to 2020
$637k
NCI NIH HHS P30 CA013148NIAID NIH HHS K08 AI113184NIAID NIH HHS R01 AI079187NIDDK NIH HHS K01 DK109006NIDDK NIH HHS P30 DK052574NIDDK NIH HHS R01 DK094995NIDDK NIH HHS R01 DK097317NIEHS NIH HHS P30 ES002109NIH HHS T32 OD010978
6 · The paper itself

Abstract

Specific gut commensal bacteria improve host health by eliciting mutualistic regulatory T (T

Identifiers

PMID28733471
PMCPMC5684094

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.