Evidence map›Paper›PMID 28733467›Full record

ArticleEndocrine-related cancer2017

Acromegaly at diagnosis in 3173 patients from the Liège Acromegaly Survey (LAS) Database.

Patrick Petrossians, Adrian F Daly, Emil Natchev, Luigi Maione, Karin Blijdorp, Mona Sahnoun-Fathallah, Renata Auriemma, Alpha M Diallo, Anna-Lena Hulting, Diego Ferone and 16 more

Abstract read
In one paragraph

Article in Endocrine-related cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Irish giants: from myth to medicine.Irish journal of medical science · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Pituitary adenoma imaging as a determinant of acromegaly diagnosis and outcomes.The Journal of clinical endocrinology and metabolism · 2026
    Review
  14. Acromegaly diagnosis.The Journal of clinical endocrinology and metabolism · 2026
    Review
  15. The acromegaly patient experience: burden of treatment and quality of life.The Journal of clinical endocrinology and metabolism · 2026
    Review
  16. Current controversies in acromegaly care.The Journal of clinical endocrinology and metabolism · 2026
    Review
  17. Genetics of familial acromegaly and pituitary gigantism.The Journal of clinical endocrinology and metabolism · 2026
    Review
  18. Changing understanding of acromegaly epidemiology and early mortality risk.The Journal of clinical endocrinology and metabolism · 2026
    Review
  19. Acromegaly complications: an update.The Journal of clinical endocrinology and metabolism · 2026
    Review
  20. Article

74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Patrick PetrossiansDepartment of EndocrinologyCHU de Liège, University of Liège, Belgium.
Adrian F DalyDepartment of EndocrinologyCHU de Liège, University of Liège, Belgium.
Emil NatchevClinical Centre of Endocrinology and GerontologyMedical University, Sofia, Bulgaria.
Luigi MaioneAPHP Endocrinology and Reproductive DiseasesParis Sud University, Le Kremlin-Bicêtre, France.
Karin BlijdorpSection of EndocrinologyDepartment of Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Mona Sahnoun-FathallahDepartment of EndocrinologyCentre de Référence des Maladies Rares d'Origine Hypophysaire, Hôpital de la Timone, Marseille, France.
Renata AuriemmaDipartimento Di Medicina Clinica e ChirurgiaSezione di Endocrinologia, University "Federico II", Naples, Italy.
Alpha M DialloDepartment of EndocrinologyCHU de Reims, France.
Anna-Lena HultingDepartment of Molecular Medicine and SurgeryKarolinska University Hospital, Stockholm, Sweden.
Diego FeroneDepartment of Internal MedicineUniversity of Genoa, Genova, Italy.
Vaclav HanaThird Department of Internal Medicine1st Faculty of Medicine, Charles University, Prague, Czech Republic.
Silvia FilipponiDepartment of Biotechnological and Applied Clinical SciencesUniversity of L'Aquila, L'Aquila, Italy and Neuromed, IRCCS, Pozzilli, Italy.
Caroline SieversDepartment of Internal MedicineEndocrinology and Clinical Chemistry, Max Planck Institute of Psychiatry, Munich, Germany.
Claudia NogueiraDepartment of Internal MedicineEndocrinology, Diabetes and Metabolism Unit, Centro Hospitalar de Trás-os-Montes e Alto Douro, Portugal.
Carmen Fajardo-MontañanaDepartment of EndocrinologyHospital Universitario de la Ribera, Alzira, Spain.
Davide CarvalhoDepartment of EndocrinologyDiabetes and Metabolism, Centro Hospitalar S. João, Faculty of Medicine, Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal.
Vaclav HanaThird Department of Internal Medicine1st Faculty of Medicine, Charles University, Prague, Czech Republic.
Günter K StallaDepartment of Internal MedicineEndocrinology and Clinical Chemistry, Max Planck Institute of Psychiatry, Munich, Germany.
Marie-Lise Jaffrain-RéaDepartment of Biotechnological and Applied Clinical SciencesUniversity of L'Aquila, L'Aquila, Italy and Neuromed, IRCCS, Pozzilli, Italy.
Brigitte DelemerDepartment of EndocrinologyCHU de Reims, France.
Annamaria ColaoDipartimento Di Medicina Clinica e ChirurgiaSezione di Endocrinologia, University "Federico II", Naples, Italy.
Thierry BrueDepartment of EndocrinologyCentre de Référence des Maladies Rares d'Origine Hypophysaire, Hôpital de la Timone, Marseille, France.
Sebastian J C M M NeggersSection of EndocrinologyDepartment of Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.
Sabina ZacharievaClinical Centre of Endocrinology and GerontologyMedical University, Sofia, Bulgaria.
Philippe ChansonAPHP Endocrinology and Reproductive DiseasesParis Sud University, Le Kremlin-Bicêtre, France.
Albert BeckersDepartment of EndocrinologyCHU de Liège, University of Liège, Belgium albert.beckers@chu.ulg.ac.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acromegaly is a rare disorder caused by chronic growth hormone (GH) hypersecretion. While diagnostic and therapeutic methods have advanced, little information exists on trends in acromegaly characteristics over time. The

Indexed as

AcromegalyDatabases, FactualFemaleHuman Growth HormoneHumansMaleMiddle AgedSurveys and QuestionnairesHuman Growth Hormoneacromegalycomorbiditydatabasedata miningdiagnosisgrowth hormoneIGF-1pituitary adenomasymptoms

Identifiers

PMID28733467
PMCPMC5574208

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.