ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
A Role for the Left Angular Gyrus in Episodic Simulation and Memory.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 9 of them syntheses that pooled it.
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Who cites it
94 citing papers in PubMed, 9 syntheses or guidelines pooled it.
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- A Systematic Review and Meta-analysis of the Neural Correlates of Direct vs. Generative Retrieval of Episodic Autobiographical Memory.Neuropsychology review · 2025Pooled it
- Effects of Healthy and Neuropathological Aging on Autobiographical Memory: A Meta-Analysis of Studies Using the Autobiographical Interview.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Pooled it
- Common and distinct correlates of construction and elaboration of episodic-autobiographical memory: An ALE meta-analysis.Cortex; a journal devoted to the study of the nervous system and behavior · 2023Pooled it
- Causal involvement of the left angular gyrus in higher functions as revealed by transcranial magnetic stimulation: a systematic review.Brain structure & function · 2023Pooled it
- Functional MRI-specific alterations in frontoparietal network in mild cognitive impairment: an ALE meta-analysis.Frontiers in aging neuroscience · 2023Pooled it
- Gray Matter Atrophy in Amnestic Mild Cognitive Impairment: A Voxel-Based Meta-Analysis.Frontiers in aging neuroscience · 2021Pooled it
- How Can Transcranial Magnetic Stimulation Be Used to Modulate Episodic Memory?: A Systematic Review and Meta-Analysis.Frontiers in psychology · 2019Pooled it
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- Examining the Role of Lateral Parietal Cortex in Emotional Distancing Using TMS.Cognitive, affective & behavioral neuroscience · 2020Trial
- Mind-body exercise improves cognitive function and modulates the function and structure of the hippocampus and anterior cingulate cortex in patients with mild cognitive impairment.NeuroImage. Clinical · 2019Trial
- Retinotopic coding organizes the interaction between internally and externally oriented brain networks.eLife · 2026Article
- Distinct and shared neurobiological patterns in PTSD and CPTSD: evidence from resting-state fMRI.BMC psychiatry · 2026Article
- Self-serving biases shape the relationship between future thinking and remembering of elections.Communications psychology · 2026Article
- Pre-service teachers' positive emotions enhance learning of students with low prior knowledge.Frontiers in psychology · 2026Article
- Hippocampal formation-cortical high-fidelity memory networks in healthy older adults during the mnemonic discrimination task.Frontiers in aging neuroscience · 2026Article
- Disentangling structure-function relationships between the human hippocampus and the whole brain using track-weighted dynamic functional connectivity.bioRxiv : the preprint server for biology · 2025Article
- Spontaneous reinstatement of episodic memories in the developing human brain.bioRxiv : the preprint server for biology · 2025Article
- Brain Cortical Area Characterization and Machine Learning-Based Measure of Rasmussen's S-R-K Model.Brain sciences · 2025Article
34 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors.
Funding
Abstract
Functional magnetic resonance imaging (fMRI) studies indicate that episodic simulation (i.e., imagining specific future experiences) and episodic memory (i.e., remembering specific past experiences) are associated with enhanced activity in a common set of neural regions referred to as the core network. This network comprises the hippocampus, medial prefrontal cortex, and left angular gyrus, among other regions. Because fMRI data are correlational, it is unknown whether activity increases in core network regions are critical for episodic simulation and episodic memory. In the current study, we used MRI-guided transcranial magnetic stimulation (TMS) to assess whether temporary disruption of the left angular gyrus would impair both episodic simulation and memory (16 participants, 10 females). Relative to TMS to a control site (vertex), disruption of the left angular gyrus significantly reduced the number of internal (i.e., episodic) details produced during the simulation and memory tasks, with a concomitant increase in external detail production (i.e., semantic, repetitive, or off-topic information), reflected by a significant detail by TMS site interaction. Difficulty in the simulation and memory tasks also increased after TMS to the left angular gyrus relative to the vertex. In contrast, performance in a nonepisodic control task did not differ statistically as a function of TMS site (i.e., number of free associates produced or difficulty in performing the free associate task). Together, these results are the first to demonstrate that the left angular gyrus is critical for both episodic simulation and episodic memory.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.