Evidence map›Paper›PMID 28733281›Full record

ArticleApplied and environmental microbiology2017

Structural and Mechanistic Insights into the Improvement of the Halotolerance of a Marine Microbial Esterase by Increasing Intra- and Interdomain Hydrophobic Interactions.

Ping-Yi Li, Yi Zhang, Bin-Bin Xie, Yan-Qi Zhang, Jie Hao, Yue Wang, Peng Wang, Chun-Yang Li, Qi-Long Qin, Xi-Ying Zhang and 4 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Ping-Yi LiInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China.
Yi ZhangInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China.
Bin-Bin XieInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China xbb@sdu.edu.cn cxl0423@sdu.edu.cn.
Yan-Qi ZhangInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China.
Jie HaoInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China.
Yue WangInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China.
Peng WangInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China.
Chun-Yang LiInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China.
Qi-Long QinInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China.
Xi-Ying ZhangInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China.
Hai-Nan SuInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China.
Mei ShiInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China.
Yu-Zhong ZhangInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China.
Xiu-Lan ChenInstitute of Marine Science and Technology, State Key Laboratory of Microbial Technology, Shandong University, Jinan, China xbb@sdu.edu.cn cxl0423@sdu.edu.cn.
Shandong University of Science and Technology · CNState Key Laboratory of Microbial TechnologyQingdao National Laboratory for Marine Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Halotolerant enzymes are beneficial for industrial processes requiring high salt concentrations and low water activity. Most halophilic proteins are evolved to have reduced hydrophobic interactions on the surface and in the hydrophobic cores for their haloadaptation. However, in this study, we improved the halotolerance of a thermolabile esterase, E40, by increasing intraprotein hydrophobic interactions. E40 was quite unstable in buffers containing more than 0.3 M NaCl, and its

Indexed as

Bacterial ProteinsCatalytic DomainEnzyme StabilityEsterasesHydrophobic and Hydrophilic InteractionsModels, MolecularProtein Structure, TertiarySeawaterSodium ChlorideBacterial ProteinsEsterasesSodium Chloridecrystal structureesterasehalotolerancehydrophobic interactionsprotein rigidity

Identifiers

PMID28733281
PMCPMC5583480
OpenAlexW2736730261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.