ReviewBMC infectious diseases2017
Exiguobacterium sp. A1b/GX59 isolated from a patient with community-acquired pneumonia and bacteremia: genomic characterization and literature review.
Review in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 36 citations in OpenAlex.
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- Isolation, Identification, and Antimicrobial Susceptibility ofVeterinary sciences · 2025Article
- Random guide-independent DNA cleavage from the Argonaute of Exiguobacterium sp. AB2.BMC microbiology · 2025Article
- Article
- Epidemiology and Antimicrobial Resistance Trends of Bloodstream Infections During and After the Implementation of the National Action Plan on Antimicrobial Resistance in Mwanza, Tanzania: A Comparative Cross-Sectional Study.Infection and drug resistance · 2025Article
- Exiguolysin, a Novel Thermolysin (M4) Peptidase fromMicroorganisms · 2024Article
- Assessment of airborne bacteria from a public health institution in Mexico City.PLOS global public health · 2024Article
- Study on active capacity and detergent application potential of low-temperature alkaline serine protease produced by new strain Exiguobacterium indicum 1.2.3.Bioresources and bioprocessing · 2023Article
- Draft Genome Sequence ofMicrobiology resource announcements · 2023Article
- Assessment of Bacteria Contaminants in Different Zones and Point Sources of Sandy Beaches in Accra, Ghana.Microbiology insights · 2023Article
- Evaluation ofHeliyon · 2023Article
- The Effects of Ventilation, Humidity, and Temperature on Bacterial Growth and Bacterial Genera Distribution.International journal of environmental research and public health · 2022Article
- Synthetic and biological surfactant effects on freshwater biofilm community composition and metabolic activity.Applied microbiology and biotechnology · 2022Article
- Polystyrene Degradation byMicroorganisms · 2022Article
- First Isolation ofPolish journal of microbiology · 2021Article
- Taxonomic and Functional Distribution of Bacterial Communities in Domestic and Hospital Wastewater System: Implications for Public and Environmental Health.Antibiotics (Basel, Switzerland) · 2021Article
- Chemical, Biological and Morphological Properties of Fine Particles during Local Rice Straw Burning Activities.International journal of environmental research and public health · 2021Article
- Performance and Application of 16S rRNA Gene Cycle Sequencing for Routine Identification of Bacteria in the Clinical Microbiology Laboratory.Clinical microbiology reviews · 2020Review
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBacterial species belonging to the genus Exiguobacterium are facultative anaerobic, non-spore-forming, Gram-positive bacilli, and rarely associated with human infections. Herein, we reported the first case of community-acquired pneumonia (CAP) and bacteremia due to Exiguobacterium spp. in China. CASE PRESENTATION: An adult male with severe CAP was hospitalized. The pathogen was isolated from his bloodstream and broncho-alveolar lavage fluid. The correct identification of the micro-organism was achieved using 16S rRNA sequencing, and its antibiotic susceptibility test was performed by microdilution method. The Whole Genome Sequencing (WGS) was used to characterize its genetic features and to elucidate its potential pathogenic mechanisms. Furthermore, its genome sequence was also compared with those of 3 publicly-available Exiguobacterium strains. A PubMed search was performed for further understanding the features of Exiguobacterium infections. Phylogenetic analysis of the 16S rRNA gene sequence showed that the strain GX59 was most closely related to Exiguobacterium AT1b (99.7%). The genome of GX59 was 2,727,929 bp in size, harbouring 2855 putative protein-coding genes, 5 rRNA operons, 37 tRNA genes and 1 tmRNA. The multiple genome comparison of 4 Exiguobacterium strains demonstrated that Exiguobacterium contained 37 genes of secretion systems, including sec, tat, FEA, Type IV Pili and competence-related DNA transformation transporter (Com). Virulence factors of the micro-organism included tlyC, NprR, MCP, Dam, which might play a critical role in causing lethal infection.
conclusionsThe study highlighted the potential pathogenicity of the genus Exiguobacterium for its unique genes encoding various virulence factors and those associated with antibiotic resistance, therefore, its clinical significance should be valued.
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