Evidence map›Paper›PMID 28732506›Full record

ReviewJournal of biomedical science2017

New insights into Blimp-1 in T lymphocytes: a divergent regulator of cell destiny and effector function.

Shin-Huei Fu, Li-Tzu Yeh, Chin-Chen Chu, B Lin-Ju Yen, Huey-Kang Sytwu

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of biomedical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 121 citations in OpenAlex.

  1. Article
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  16. Plasma exosomal miR-150-3p,American journal of cancer research · 2025
    Article
  17. Review
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  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Shin-Huei FuDepartment and Graduate Institute of Microbiology and Immunology, National Defense Medical Center, 161, Section 6, Min-Chuan East Road, Neihu District, Taipei, 11490, Taiwan.
Li-Tzu YehDepartment and Graduate Institute of Microbiology and Immunology, National Defense Medical Center, 161, Section 6, Min-Chuan East Road, Neihu District, Taipei, 11490, Taiwan.
Chin-Chen ChuDepartment of Anesthesiology, Chi Mei Medical Center, Tainan, 71104, Taiwan. chinchen.chu@gmail.com.
B Lin-Ju YenInstitute of Cellular and System Medicine, National Health Research Institutes, Zhunan, 35053, Taiwan.
Huey-Kang SytwuDepartment and Graduate Institute of Microbiology and Immunology, National Defense Medical Center, 161, Section 6, Min-Chuan East Road, Neihu District, Taipei, 11490, Taiwan. sytwu@ndmctsgh.edu.tw.
National Defense Medical Center · TWChi Mei Medical Center · TWNational Health Research Institutes · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

B lymphocyte-induced maturation protein-1 (Blimp-1) serves as a master regulator of the development and function of antibody-producing B cells. Given that its function in T lymphocytes has been identified within the past decade, we review recent findings with emphasis on its role in coordinated control of gene expression during the development, differentiation, and function of T cells. Expression of Blimp-1 is mainly confined to activated T cells and is essential for the production of interleukin (IL)-10 by a subset of forkhead box (Fox)p3

Indexed as

Lymphocyte ActivationPositive Regulatory Domain I-Binding Factor 1T-LymphocytesPositive Regulatory Domain I-Binding Factor 1PRDM1 protein, humanBcl-6Blimp-1CD4+ T lymphocytesCD8+ T lymphocytesInterleukinsPrdm1Regulatory T cellsSTATsT follicular helper cellsT helper cells

Identifiers

PMID28732506
PMCPMC5520377
OpenAlexW2737010569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.