ArticleArthritis care & research2018
Trends in Hospitalizations for Serious Infections in Patients With Rheumatoid Arthritis in the US Between 1993 and 2013.
Article in Arthritis care & research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Development and Validation of a 28-Day Mortality Prediction Model for Patients with Sepsis Complicated by Autoimmune Diseases Using Two Machine Learning Methods.Journal of inflammation research · 2026Article
- Sepsis in Autoimmune Rheumatic Diseases: Risk Factors, Pathophysiology, and Outcomes.Risk management and healthcare policy · 2026Review
- Evaluation of serious infections, including Mycobacterium tuberculosis, during treatment with biologic disease-modifying anti-rheumatic drugs: does line of therapy matter?Rheumatology (Oxford, England) · 2024Article
- Prognostic impacts of repeated sepsis in intensive care unit on autoimmune disease patients: a retrospective cohort study.BMC infectious diseases · 2024Article
- Serious Infection Rates Among Patients with Select Autoimmune Conditions: A Claims-Based Retrospective Cohort Study from Taiwan and the USA.Rheumatology and therapy · 2023Article
- Infection-related hospitalisation in young adults with systemic lupus erythematosus: data from the National Inpatient Sample.Lupus science & medicine · 2023Article
- Hospitalized Infections in Patients With Rheumatic Disease Hospitalizations in Alaska, 2015-2018.ACR open rheumatology · 2023Article
- The prognostic impact of rheumatoid arthritis in sepsis: a population-based analysis.Acute and critical care · 2022Article
- Hospitalizations Associated With Rheumatic Disease in Alaska, 2015-2018.ACR open rheumatology · 2022Article
- Incidence, mortality, and national costs of hospital admissions for potentially preventable infections in patients with rheumatoid arthritis.Clinical rheumatology · 2021Article
- Mortality of Sepsis in Patients With Rheumatoid Arthritis: A Single-Center Retrospective Analysis and Comparison With a Control Group.Journal of intensive care medicine · 2021Article
- Trends in Hospitalization Rates, Major Causes of Hospitalization, and In-Hospital Mortality in Rheumatoid Arthritis in the United States From 2000 to 2014.ACR open rheumatology · 2020Article
- Serious infections in people with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA): a time-trend national US study.Clinical rheumatology · 2020Article
- Serious infections in people with systemic sclerosis: a national US study.Arthritis research & therapy · 2020Article
- [Treatment of infections in the critically ill under immunosuppression : What must be considered?]Zeitschrift fur Rheumatologie · 2019Review
- The increase of sepsis-related mortality in Italy: a nationwide study, 2003-2015.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019Article
- The Burden of Frailty Among U.S. Veterans and Its Association With Mortality, 2002-2012.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019Article
- Prediction of infection risk in rheumatoid arthritis patients treated with biologics: are we any closer to risk stratification?Current opinion in rheumatology · 2019Review
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Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThe epidemiology of hospitalizations with infections among patients with rheumatoid arthritis (RA) is unknown, despite an increase in RA treatments that confer a risk of infection.
methodsWe examined National Inpatient Sample data from 1993-2013. We identified hospitalizations among adults with RA, defined by International Classification of Diseases, Ninth Revision, Clinical Modification codes (714.xx) in any secondary diagnosis field. We evaluated 5 infections as the primary diagnosis: pneumonia, sepsis, urinary tract infection (UTI), skin and soft tissue infections (SSTIs), and opportunistic infections (OIs). The primary outcome was the proportion of hospitalizations for each infection among all hospitalizations with a secondary diagnosis of RA.
resultsThere were 792,921 hospitalizations for infection with a secondary diagnosis of RA, with the rates increasing from 90 to 206 per 100,000 persons from 1993-2013. The proportion of hospitalizations decreased for pneumonia (from 5.4% to 4.6%), UTI (from 0.4% to 0.38%), and OIs (from 0.44% to 0.26%). The proportion of hospitalizations for SSTIs increased slightly (from 2.3% to 2.5%), while hospitalizations for sepsis more than tripled (from 1.9% to 6.4%).
conclusionBetween 1993 and 2013, the proportion of hospitalizations for infections among RA patients appeared to decline for pneumonia and OIs, with a slight decrease in UTI, a slight increase in SSTIs, and a substantial increase in hospitalizations with sepsis. Our results are consistent with previous reports that the sensitivity of sepsis coding has increased over time.
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