Evidence map›Paper›PMID 28731788›Full record

ArticleJournal of dental research2017

Identification of Osr2 Transcriptional Target Genes in Palate Development.

X Fu, J Xu, P Chaturvedi, H Liu, R Jiang, Y Lan

Abstract read
In one paragraph

Article in Journal of dental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Genetic architecture of craniofacial morphogenesis: roles ofFrontiers in cell and developmental biology · 2026
    Review
  5. Article
  6. Article
  7. Review
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  9. Review
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  11. Article
  12. Review
  13. Article
  14. Article
  15. A Potential Role of Semaphorin 3A during Orthodontic Tooth Movement.International journal of molecular sciences · 2021
    Article
  16. Article
  17. Frontiers in cell and developmental biology · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

X Fu1 Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
J Xu1 Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
P Chaturvedi1 Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
H Liu1 Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
R Jiang1 Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Y Lan1 Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Cincinnati Children's Hospital Medical Center · US

Funding

MOLECULAR GENETIC ANALYSIS OF CRANIOFACIAL DEVELOPMENTR01DE013681 · NIDCR · UNIVERSITY OF ROCHESTER · PI JIANG, RULANG · 2000 to 2014
$6.3M
Molecular Patterning of Mammalian DentitionR01DE018401 · NIDCR · UNIVERSITY OF ROCHESTER · PI JIANG, RULANG · 2009 to 2017
$3.4M
NIDCR NIH HHS R01 DE013681NIDCR NIH HHS R01 DE018401
6 · The paper itself

Abstract

Previous studies have identified the odd-skipped related 2 (Osr2) transcription factor as a key intrinsic regulator of palatal shelf growth and morphogenesis. However, little is known about the molecular program acting downstream of Osr2 in the regulation of palatogenesis. In this study, we isolated palatal mesenchyme cells from embryonic day 12.5 (E12.5) and E13.5 Osr2

Indexed as

AnimalsCell DifferentiationCell ProliferationCells, CulturedGene Expression Regulation, DevelopmentalImmunoprecipitationIn Situ HybridizationMiceMice, Inbred StrainsMorphogenesisPalateReal-Time Polymerase Chain ReactionSignal TransductionTranscription FactorsOsr2 protein, mouseTranscription Factorscleft palatecraniofacial biologygene expressionmorphogenesisosteogenesissignal transduction

Identifiers

PMID28731788
PMCPMC5652858
OpenAlexW2738558791

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.