ArticleJournal of Alzheimer's disease : JAD2017
Challenges and Considerations Related to Studying Dementia in Blacks/African Americans.
Article in Journal of Alzheimer's disease : JAD, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 56 citations in OpenAlex.
- Association of tailpipe-related and nontailpipe-related air pollution exposure with neuroimaging outcomes.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Development and Preliminary Validation of Standardized Regression-Based Change Scores as Measures of Transitional Cognitive Decline.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Article
- ARTS is associated with vascular risk factors, MCI, dementia, and stroke.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Bridging the gap: Multi-omics profiling of brain tissue in Alzheimer's disease and older controls in multi-ethnic populations.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Cerebral arteriolosclerosis, lacunar infarcts, and cognition in older Black adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Bridging the Gap: Multi-Omics Profiling of Brain Tissue in Alzheimer's Disease and Older Controls in Multi-Ethnic Populations.bioRxiv : the preprint server for biology · 2024Article
- Attitudes and Perceptions about Brain Donation Among African Americans: Implications for Recruitment into Alzheimer's Disease Research.Journal of Alzheimer's disease : JAD · 2024Article
- Do Associations Between Vascular Risk and Mild Cognitive Impairment Vary by Race?Journal of aging and health · 2023Article
- Bringing Health Care Equity to Diverse and Underserved Populations in Sleep Medicine and Research Through a Digital Health Equity Framework.Sleep medicine clinics · 2023Review
- LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry.Journal of neuropathology and experimental neurology · 2023Article
- Quantification of race/ethnicity representation in Alzheimer's disease neuroimaging research in the USA: a systematic review.Communications medicine · 2023Review
- The neuropathological landscape of Hispanic and non-Hispanic White decedents with Alzheimer disease.Acta neuropathologica communications · 2023Article
- A Qualitative Examination of Knowledge, Experiences, and Considerations of PET Brain Scan Participation Among Older Black and Latino Adults.Journal of Alzheimer's disease : JAD · 2023Article
- Including Socially Isolated Black, Older Old Adults (Aged 80 and Above) with and without Mild Cognitive Impairment in a Clinical Trial: Recruitment Strategies and Perspectives.Journal of multidisciplinary healthcare · 2023Article
- Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities.Neurobiology of disease · 2022Article
- Black and White individuals differ in dementia prevalence, risk factors, and symptomatic presentation.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Article
- A cultural approach to dementia - insights from US Latino and other minoritized groups.Nature reviews. Neurology · 2022Review
- Utilizing community engagement studios to inform clinical trial design at a Center of Excellence for Alzheimer's Disease.Journal of clinical and translational science · 2022Article
- Cancer and Vascular Comorbidity Effects on Dementia Risk and Neuropathology in the Oldest-Old.Journal of Alzheimer's disease : JAD · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 5 institutions in 1 country.
Funding
Abstract
Blacks/African Americans have been reported to be ∼2-4 times more likely to develop clinical Alzheimer's disease (AD) compared to Whites. Unfortunately, study design challenges (e.g., recruitment bias), racism, mistrust of healthcare providers and biomedical researchers, confounders related to socioeconomic status, and other sources of bias are often ignored when interpreting differences in human subjects categorized by race. Failure to account for these factors can lead to misinterpretation of results, reification of race as biology, discrimination, and missed or delayed diagnoses. Here we provide a selected historical background, discuss challenges, present opportunities, and suggest considerations for studying health outcomes among racial/ethnic groups. We encourage neuroscientists to consider shifting away from using biologic determination to interpret data, and work instead toward a paradigm of incorporating both biological and socio-environmental factors known to affect health outcomes with the goal of understanding and improving dementia treatments for Blacks/African Americans and other underserved populations.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.