Evidence map›Paper›PMID 28731031›Full record

ArticleCell research2017

NLRP9b: a novel RNA-sensing inflammasome complex.

Chinh Ngo, Si Ming Man

Open access · bronzeAbstract readComment
In one paragraph

Article in Cell research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Role of Nod-like Receptors inMicroorganisms · 2026
    Review
  3. Review
  4. NLRP inflammasomes in health and disease.Molecular biomedicine · 2024
    Review
  5. Article
  6. Review
  7. Review
  8. Molecular biology of autoinflammatory diseases.Inflammation and regeneration · 2021
    Review
  9. Review
  10. Cytosolic Recognition of Microbes and Pathogens: Inflammasomes in Action.Microbiology and molecular biology reviews : MMBR · 2018
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chinh NgoDepartment of Immunology and Infectious Disease, The John Curtin School of Medical Research, Australian National University, Canberra, 2601, Australia.
Si Ming ManDepartment of Immunology and Infectious Disease, The John Curtin School of Medical Research, Australian National University, Canberra, 2601, Australia.
Australian National University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammasome sensors recognize pathogens and danger signals and assemble an immune signaling complex, which induces the secretion of pro-inflammatory cytokines IL-1β and IL-18, and pyroptosis. A new study published in Nature now describes a new inflammasome sensor NLRP9b in intestinal epithelial cells, which in concert with the RNA sensor DHX9, recognize short dsRNA from Rotavirus.

Indexed as

InflammasomesRotavirus InfectionsDEAD-box RNA HelicasesEpithelial CellsHumansInterleukin-1betaNeoplasm ProteinsPyroptosisDEAD-box RNA HelicasesDHX9 protein, humanInflammasomesInterleukin-1betaNeoplasm Proteins

Identifiers

PMID28731031
PMCPMC5674164
OpenAlexW2738600130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.