Evidence map›Paper›PMID 28730849›Full record

Trial reportClinical rehabilitation2018

Treadmill training to improve mobility for people with sub-acute stroke: a phase II feasibility randomized controlled trial.

Gillian D Baer, Lisa G Salisbury, Mark T Smith, Jane Pitman, Martin Dennis

Open access · hybridAbstract readClinical Trial, Phase IIComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Clinical rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Physical fitness training for stroke patients.The Cochrane database of systematic reviews · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Gillian D Baer1 Department of Physiotherapy, Queen Margaret University, Edinburgh, UK.
Lisa G Salisbury1 Department of Physiotherapy, Queen Margaret University, Edinburgh, UK.
Mark T Smith2 NHS Lothian, Edinburgh, UK.
Jane Pitman2 NHS Lothian, Edinburgh, UK.
Martin Dennis3 Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK.
NHS Lothian · GBQueen Margaret University · GBUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis phase II study investigated the feasibility and potential effectiveness of treadmill training versus normal gait re-education for ambulant and non-ambulant people with sub-acute stroke delivered as part of normal clinical practice.

designA single-blind, feasibility randomized controlled trial.

settingFour hospital-based stroke units. SUBJECTS: Participants within three months of stroke onset.

interventionsParticipants were randomized to treadmill training (minimum twice weekly) plus normal gait re-education or normal gait re-education only (control) for up to eight weeks. MAIN MEASURES: Measures were taken at baseline, after eight weeks of intervention and at six-month follow-up. The primary outcome was the Rivermead Mobility Index. Other measures included the Functional Ambulation Category, 10-metre walk, 6-minute walk, Barthel Index, Motor Assessment Scale, Stroke Impact Scale and a measure of confidence in walking.

resultsIn all, 77 patients were randomized, 39 to treadmill and 38 to control. It was feasible to deliver treadmill training to people with sub-acute stroke. Only two adverse events occurred. No statistically significant differences were found between groups. For example, Rivermead Mobility Index, median (interquartile range (IQR)): after eight weeks treadmill 5 (4-9), control 6 (4-11) p = 0.33; or six-month follow-up treadmill 8.5 (3-12), control 8 (6-12.5) p = 0.42. The frequency and intensity of intervention was low.

conclusionTreadmill training in sub-acute stroke patients was feasible but showed no significant difference in outcomes when compared to normal gait re-education. A large definitive randomized trial is now required to explore treadmill training in normal clinical practice.

Indexed as

Walking SpeedAgedExercise TestExercise TherapyFeasibility StudiesFemaleFollow-Up StudiesGait Disorders, NeurologicHumansMaleMiddle AgedMobility LimitationPsychomotor PerformanceRisk AssessmentSingle-Blind MethodStrokeexerciseGaitparticipationphysical therapyrehabilitationstroketreadmill

Identifiers

PMID28730849
PMCPMC5777545
OpenAlexW2738582677

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.