SynthesisJournal of neurology2017
Early trigeminal nerve involvement in Listeria monocytogenes rhombencephalitis: case series and systematic review.
Synthesis in Journal of neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28 citing papers in PubMed, 50 citations in OpenAlex.
- An unusual case of neglected CSOM presenting with perineural spread along seventh/eighth cranial nerves to form cerebellar peduncle abscess: A case report.Radiology case reports · 2026Article
- Listerial rhombencephalitis diagnosed by repeat blood culture despite negative CSF PCR: a case report.ASM case reports · 2026Article
- Bickerstaff brainstem encephalitis: a 13-case series and literature review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Article
- A Rare Cause of Acute Dysphagia: Listeria Rhombencephalitis.European journal of case reports in internal medicine · 2026Article
- Bioprotective Strategies to ControlInternational journal of molecular sciences · 2025Review
- Review
- Plasma cell-free DNA testing in diagnosing Listeria rhombencephalitis in a CSF PCR-negative patient: a case report.BMJ neurology open · 2025Article
- Clinical Presentations and Nosocomial Infections of Neurolisteriosis.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025Review
- Case Report: Pediatric pontine abscess and ecthyma gangrenosum due toFrontiers in pediatrics · 2025Article
- Cranial nerves bridging the middle ear and cerebellum causing cerebellar peduncle abscess: A case report.Acta radiologica open · 2024Article
- Computed tomography and magnetic resonance imaging findings in central nervous system listeriosis.Neuroradiology · 2024Article
- Article
- A rare case of Listeria rhombencephalitis with a sudden onset and unusual brain MRI features.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Epidemiology, clinical and imaging features of rhombencephalitis caused by L. monocytogenes. A retrospective observational study.Revista de neurologia · 2023Observational
- Human Listeriosis.Clinical microbiology reviews · 2023Review
- Application of metagenomic next-generation sequencing for the diagnosis of intracranial infection ofAnnals of translational medicine · 2022Article
- Pathogenicity and virulence ofVirulence · 2021Article
- Rhombencephalitis due toThe Journal of international medical research · 2021Review
- Article
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Listeria monocytogenes is associated with rhombencephalitis. However, the exact mechanisms of brainstem invasion remains poorly understood. Here, we demonstrate clinical and radiological data suggesting that Listeria may invade the brainstem via the trigeminal nerve. Three females (41, 64 and 70 years) with culture proven L. monocytogenes bacteremia and rhombencephalitis were investigated in the period of 2014-16. T2-weighted and contrast-enhanced T1-weighted MRI revealed a cerebellopontine abscess in all three patients, including the involvement of the trigeminal nerve root. In two patients, MRI also revealed selective contrast enhancement of the sensory trigeminal tract in the pons and medulla oblongata. Prior to any other neurological symptoms, two patients complained of hypoesthesia and a tingling sensation in the ipsilateral half of the face, consistent with sensory trigeminal nerve dysfunction on that side. In addition, we identified another 120 cases of Listeria rhombencephalitis following a systematic review. Cranial nerves VII, V, IX, and X, respectively, medulla oblongata, cerebellum and pons, were the most frequently involved brain structures. The present clinical and radiological findings corroborate earlier data from animal experiments, indicating that L. monocytogenes may be capable of retrograde intra-axonal migration along the cranial nerves. We suggest that in a subset of patients with rhombencephalitis L. monocytogenes enters the cerebellopontine angle through the trigeminal nerve, invading the brainstem via the sensory trigeminal nuclei.
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