Evidence map›Paper›PMID 28730441›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2017

Preparation and Optimization of Lipid-Like Nanoparticles for mRNA Delivery.

Bin Li, Yizhou Dong

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Delivering CRISPR to the HIV-1 reservoirs.Frontiers in microbiology · 2024
    Review
  4. Review
  5. Article
  6. Review
  7. Ionizable lipid nanoparticles encapsulating barcoded mRNA for accelerated in vivo delivery screening.Journal of controlled release : official journal of the Controlled Release Society · 2019
    Article
  8. Nanoscale platforms for messenger RNA delivery.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2019
    Review
  9. Review
  10. Lipid Polymer Hybrid Nanomaterials for mRNA Delivery.Cellular and molecular bioengineering · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bin LiDivision of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, 496 W. 12th Ave., Columbus, OH, 43210, USA.
Yizhou DongDivision of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, The Ohio State University, 496 W. 12th Ave., Columbus, OH, 43210, USA. dong.525@osu.edu.

Funding

Cell-specific and multifunctional drug formulations for in vivo deliveryR35GM119679 · NIGMS · OHIO STATE UNIVERSITY · PI DONG, YIZHOU · 2016 to 2020
$1.9M
NIGMS NIH HHS R35 GM119679
6 · The paper itself

Abstract

Lipid-like nanoparticles (LLNs) have shown great promise for nucleic acid delivery. Recently, we have developed N

Indexed as

Gene Transfer TechniquesLipidsNanoparticlesCell LineCell SurvivalHumansPolyethylene GlycolsRNA, MessengerTransfectionLipidsPolyethylene GlycolsRNA, MessengerDelivery efficiencyLipid-like nanoparticles (LLNs)mRNA deliveryOptimizationOrthogonal array design

Identifiers

PMID28730441
PMCPMC5921050

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.