Evidence map›Paper›PMID 28730166›Full record

ArticleOpen medicine (Warsaw, Poland)2017

Impact of Chromosomal Rearrangement upon DNA Methylation Patterns in Leukemia.

Hyang-Min Byun, Shahrooz Eshaghian, Dan Douer, Jonathen Trent, Guillermo Garcia-Manero, Ravi Bhatia, Kim Siegmund, Allen S Yang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open medicine (Warsaw, Poland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Hyang-Min ByunHuman Nutrition Research Centre, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, NE4 5PLUnited Kingdom.
Shahrooz EshaghianJane Anne Nohl Division of Hematology; University of Southern California, Los Angeles, CA, USA.
Dan DouerJane Anne Nohl Division of Hematology; University of Southern California, Los Angeles, CA, USA.
Jonathen TrentDepartment of Sarcoma, University of Texas-MD Anderson Cancer Center, Houston, TX, USA.
Guillermo Garcia-ManeroDepartment of Leukemia, University of Texas-MD Anderson Cancer Center, Houston, TX, USA.
Ravi BhatiaDepartment of Hematology, City of Hope Cancer Center, Duarte, CA, USA.
Kim SiegmundDepartment of Preventive Medicine, University of Southern California, Los Angeles, CA, USA.
Allen S YangJane Anne Nohl Division of Hematology; University of Southern California, Los Angeles, CA, USA.
University of Southern California · USThe University of Texas MD Anderson Cancer Center · USCity of Hope · USNewcastle University · GBThe Jane Goodall Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genomic instability, including genetic mutations and chromosomal rearrangements, can lead to cancer development. Aberrant DNA methylation occurs commonly in cancer cells. The aim of this study is to determine the effects of a specific chromosomal lesion the

Indexed as

5-azacytidineAcute Lymphoblastic LeukemiaAcute Promyelocytic LeukemiaChronic Myelogenous LeukemiaDNA methylationGastrointestinal Stromal TumorPhiladelphia Chromosome

Identifiers

PMID28730166
PMCPMC5444343
OpenAlexW2610193786

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.