Evidence map›Paper›PMID 28730152›Full record

ArticleToxics2016

Zebrafish Get Connected: Investigating Neurotransmission Targets and Alterations in Chemical Toxicity.

Katharine A Horzmann, Jennifer L Freeman

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 2 syntheses or guidelines pooled it, 182 citations in OpenAlex.

  1. Pooled it
  2. Toxic Effects of Glyphosate on the Nervous System: A Systematic Review.International journal of molecular sciences · 2022
    Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. A venom fraction from the Philippine tarantula (The journal of venomous animals and toxins including tropical diseases · 2026
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Disruption ofThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  18. Article
  19. Review
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Katharine A HorzmannSchool of Health Sciences, Purdue University, West Lafayette, IN 47907, USA.
Jennifer L FreemanSchool of Health Sciences, Purdue University, West Lafayette, IN 47907, USA.
Purdue University West Lafayette · US

Funding

Molecular biomarkers of exposure to an endocrine disrupting herbicideR15ES019137 · NIEHS · PURDUE UNIVERSITY · PI FREEMAN, JENNIFER L. · 2010 to 2013
$891k
NIEHS NIH HHS R15 ES019137
6 · The paper itself

Abstract

Neurotransmission is the basis of neuronal communication and is critical for normal brain development, behavior, learning, and memory. Exposure to drugs and chemicals can alter neurotransmission, often through unknown pathways and mechanisms. The zebrafish (

Indexed as

acetylcholinedopamineGABAglutamateneurotoxicologyneurotransmissionneurotransmittersnorepinephrineserotoninzebrafish

Identifiers

PMID28730152
PMCPMC5515482
OpenAlexW2513935446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.