ArticleBrain and behavior2017
Relationship between cerebellar structure and emotional memory in depression.
Article in Brain and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Smaller total and subregional cerebellar volumes in posttraumatic stress disorder: a mega-analysis by the ENIGMA-PGC PTSD workgroup.Molecular psychiatry · 2024Pooled it
- The Anatomical Connections of Nucleus Accumbens with Brainstem and Cerebellum in the Rat and Human Subjects.Cerebellum (London, England) · 2026Article
- 3DViT-GAT: a unified atlas-based 3D vision transformer and graph learning framework for major depressive disorder detection using structural MRI data.Scientific reports · 2026Article
- Family history, inflammation, and cerebellum in major depression: a combined VBM and dynamic functional connectivity study.Translational psychiatry · 2025Article
- The different impacts of functional network centrality and connectivity on the complexity of brain signals in healthy control and first-episode drug-naïve patients with major depressive disorder.Brain imaging and behavior · 2025Article
- Altered dynamic functional connectivity in antagonistic state in first-episode, drug-naïve patients with major depressive disorder.BMC psychiatry · 2024Article
- An objective quantitative diagnosis of depression using a local-to-global multimodal fusion graph neural network.Patterns (New York, N.Y.) · 2024Article
- Modulation of habenular and nucleus accumbens functional connectivity by ketamine in major depression.Brain and behavior · 2024Article
- Consensus Paper: Cerebellum and Ageing.Cerebellum (London, England) · 2024Review
- Altered brain function and structure pre- and post- COVID-19 infection: a longitudinal study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Disruptive and complementary effects of depression symptoms on spontaneous brain activity in the subcortical vascular mild cognitive impairment.Frontiers in aging neuroscience · 2024Article
- Resting-state functional connectivity of the cerebellum-cerebrum in older women with depressive symptoms.BMC psychiatry · 2023Article
- Cerebro-cerebellar functional neuroplasticity mediates the effect of electric field on electroconvulsive therapy outcomes.Translational psychiatry · 2023Article
- An ecological animal model of subthreshold depression in adolescence: behavioral and resting stateTranslational psychiatry · 2022Article
- Article
- 7T ultra-high-field neuroimaging for mental health: an emerging tool for precision psychiatry?Translational psychiatry · 2022Review
- Enhanced cerebro-cerebellar functional connectivity reverses cognitive impairment following electroconvulsive therapy in major depressive disorder.Brain imaging and behavior · 2021Article
- Aberrant Resting-State Brain Function in Adolescent Depression.Frontiers in psychology · 2020Article
- Volumetric Deficit Within the Fronto-Limbic-Striatal Circuit in First-Episode Drug Naïve Patients With Major Depression Disorder.Frontiers in psychiatry · 2020Article
- Altered Regional Cerebral Blood Flow Associated with Mood and Sleep in Shift Workers: Cerebral Perfusion Magnetic Resonance Imaging Study.Journal of clinical neurology (Seoul, Korea) · 2019Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA few studies have been conducted on the relationship between cerebellar volume and emotional memory or clinical severity in major depressive disorder (MDD). In this study, we aimed to compare the volume and density of the cerebellar gray matter (GM) in patients with MDD and in healthy controls (HCs) and explore the association between these cerebellar parameters and measurements of emotional memory and clinical severity.
methodVoxel-based morphometry (VBM) and Individual Brain Atlases using Statistical Parametric Mapping (IBASPM) were used to assess GM density and volume in the cerebellum, respectively, in patients with MDD and the HCs. Indicators of emotional memory performance were measured, including the hit rate (HR), rate of false alarm (FA), precision (Pr = HR - FA) and emotional memory enhancement [∆Pr = Pr(emotion) - Pr(neutral)] values. Beck Depression Inventory (BDI) scores were used to measure the severity of depression.
resultsIn the patients with MDD, the GM density was decreased in three cerebellar cortical regions and increased in three cerebellar cortical regions (
conclusionsEmotional memory and the severity of depressive symptoms are associated with structural changes in both the posterior and anterior GM regions in the cerebellum in patients with MDD. These findings could be useful for improving our understanding of the neurobiological mechanisms underlying emotional memory and explaining the abnormalities of the neural correlates that are associated with MDD.
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