Evidence map›Paper›PMID 28729937›Full record

ArticleBrain and behavior2017

Manganese-enhanced magnetic resonance imaging combined with electrophysiology in the evaluation of visual pathway in experimental rat models with monocular blindness.

Zuohua Tang, Jie Wang, Zebin Xiao, Xinghuai Sun, Xiaoyuan Feng, Weijun Tang, Qian Chen, Lingjie Wu, Rong Wang, Yufeng Zhong and 2 more

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Zuohua TangDepartment of Radiology Eye and ENT Hospital of Shanghai Medical School Fudan University Shanghai China.ORCID 0000-0003-4687-5905
Jie WangDepartment of Radiotherapy Eye and ENT Hospital of Shanghai Medical School Fudan University Shanghai China.
Zebin XiaoDepartment of Radiology Eye and ENT Hospital of Shanghai Medical School Fudan University Shanghai China.
Xinghuai SunState Key Laboratory of Medical Neurobiology Department of Ophthalmology Eye and ENT Hospital of Shanghai Medical School Institutes of Brain Science Fudan University Shanghai China.
Xiaoyuan FengDepartment of Radiology Huashan Hospital of Shanghai Medical School Fudan University Shanghai China.
Weijun TangDepartment of Radiology Huashan Hospital of Shanghai Medical School Fudan University Shanghai China.
Qian ChenState Key Laboratory of Medical Neurobiology Department of Ophthalmology Eye and ENT Hospital of Shanghai Medical School Institutes of Brain Science Fudan University Shanghai China.
Lingjie WuDepartment of Otolaryngology Eye and ENT Hospital of Shanghai Medical School Fudan University Shanghai China.
Rong WangDepartment of Radiology Eye and ENT Hospital of Shanghai Medical School Fudan University Shanghai China.
Yufeng ZhongDepartment of Radiology Eye and ENT Hospital of Shanghai Medical School Fudan University Shanghai China.
Wentao WangCentral Laboratory Eye and ENT Hospital of Shanghai Medical School Fudan University Shanghai China.
Jianfeng LuoHealth Statistics Shanghai Medical School Fudan University Shanghai China.
Eye & ENT Hospital of Fudan University · CNShanghai Medical College of Fudan University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOur study aimed to explore the feasibility of manganese-enhanced magnetic resonance imaging (MEMRI) combined with visual evoked potentials (VEP) and auditory evoked visual cortex responses (AVR) in evaluating for the establishment of visual/auditory compensatory pathways after monocular blindness. MATERIALS AND

methodsA total of 14 healthy neonatal male Sprague-Dawley rats were randomly divided into two groups (

resultsThe VEP test indicated complete visual loss after ON transection. In the monocularly blind rats, the contrast-to-noise ratio (CNR) of ON, optic tract (OT), lateral geniculate nucleus (LGN), superior colliculus (SC), optic radiation (OR) and visual cortex (VC) of visual pathway projected from the left eye was significantly higher than that of the right pathway (

conclusionMEMRI combined with electrophysiology, including VEP and AVR, may be potentially helpful in the evaluation of the possible generation of new visual/auditory compensatory pathways after monocular blindness.

Indexed as

AnimalsBlindnessElectrophysiologyEvoked Potentials, VisualMagnetic Resonance ImagingMaleManganeseRatsRats, Sprague-DawleyVisual CortexVisual PathwaysManganeseauditory evoked visual cortex responsesmanganese‐enhanced MRImonocular blindnessvisual evoked potentialsvisual pathway

Identifiers

PMID28729937
PMCPMC5516605
OpenAlexW2619212202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.